| Tag |
Content |
| dbPAF ID |
dbPAF-0000980 |
| Uniprot Accession |
O15498; YKT6_HUMAN; B4DR94; Q53F01; Q6FGU9; Q6IB15;
|
| Genbank Protein ID |
NP_006546.1;
|
| Genbank Nucleotide ID |
NM_006555.3;
|
| Protein Name |
Synaptobrevin homolog YKT6 |
| Protein Synonyms/Alias |
|
| Gene Name |
YKT6 |
| Gene Synonyms/Alias |
|
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.Functional Description
Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MKLYSLSVLY KGEAKVVLLK AAYDVSSFSF FQRSSVQEFM TFTSQLIVER SSKGTRASVK 60
EQDYLCHVYV RNDSLAGVVI ADNEYPSRVA FTLLEKVLDE FSKQVDRIDW PVGSPATIHY 120
PALDGHLSRY QNPREADPMT KVQAELDETK IILHNTMESL LERGEKLDDL VSKSEVLGTQ 180
SKAFYKTARK QNSCCAIM
199Fasta Sequence
>O15498|YKT6|Homo sapiens(Human)
MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM
|
| Keyword |
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0564--Palmitate
KW-0636--Prenylation
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0808--Transferase
KW-0813--Transport
|
| Interpro |
IPR011012--Longin-like_dom
IPR010908--Longin_dom
IPR001388--Synaptobrevin
|
| PROSITE |
PS50859--LONGIN
PS50892--V_SNARE
|
| Pfam |
PF13774--Longin
PF00957--Synaptobrevin
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0030659--C:cytoplasmic vesicle membrane
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005794--C:Golgi apparatus
GO:0000139--C:Golgi membrane
GO:0005887--C:integral component of plasma membrane
GO:0005739--C:mitochondrion
GO:0031201--C:SNARE complex
GO:0019706--F:protein-cysteine S-palmitoyltransferase activity
GO:0005484--F:SNAP receptor activity
GO:0000149--F:SNARE binding
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006887--P:exocytosis
GO:0015031--P:protein transport
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0006904--P:vesicle docking involved in exocytosis
GO:0006906--P:vesicle fusion
GO:0006903--P:vesicle targeting
|
