dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000972
Uniprot Accession O15479; MAGB2_HUMAN; O75860;
Genbank Protein ID NP_002355.2; XP_011543814.1;
Genbank Nucleotide ID NM_002364.4; XM_011545512.1;
Protein Name Melanoma-associated antigen B2
Protein Synonyms/Alias Cancer/testis antigen 3.2;CT3.2;DSS-AHC critical interval MAGE superfamily 6;DAM6;MAGE XP-2 antigen;MAGE-B2 antigen;
Gene Name MAGEB2
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
42EEEAPCCSSSVSGGAdbPTM 3.0;Phospho.ELM 9.0;curated18669648; 16381945; 23193290; 22817900
44EAPCCSSSVSGGAASdbPTM 3.0;Phospho.ELM 9.0;curated18669648; 16381945; 23193290; 22817900
51SVSGGAASSSPAAGIdbPTM 3.0;Phospho.ELM 9.0;curated18669648; 16381945; 23193290; 22817900
53SGGAASSSPAAGIPQdbPTM 3.0;curated18669648; 16381945; 23193290; 22817900
77AAAAAGVSSTKSKKGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 18988627; 19060867; 22135298;
78AAAAGVSSTKSKKGAdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 22135298; 22817900;
79AAAGVSSTKSKKGAKcurated23917254
81AGVSSTKSKKGAKSHPhosphoSitePlus22135298
95HQGEKNASSSQASTSPhosphoSitePlus22135298
105QASTSTKSPSEDPLTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 18988627; 22135298; 19366988;
112SPSEDPLTRKSGSLVcurated23186163
115EDPLTRKSGSLVQFLcurated26074081
117PLTRKSGSLVQFLLYdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 22135298; 22817900;
124SLVQFLLYKYKIKKSPhosphoSitePlus;curated22135298; 26074081
131YKYKIKKSVTKGEMLPhosphoSitePlus22135298
Sequence
(Fasta)		MPRGQKSKLR AREKRRKARD ETRGLNVPQV TEAEEEEAPC CSSSVSGGAA SSSPAAGIPQ 60
EPQRAPTTAA AAAAGVSSTK SKKGAKSHQG EKNASSSQAS TSTKSPSEDP LTRKSGSLVQ 120
FLLYKYKIKK SVTKGEMLKI VGKRFREHFP EILKKASEGL SVVFGLELNK VNPNGHTYTF 180
IDKVDLTDEE SLLSSWDFPR RKLLMPLLGV IFLNGNSATE EEIWEFLNML GVYDGEEHSV 240
FGEPWKLITK DLVQEKYLEY KQVPSSDPPR FQFLWGPRAY AETSKMKVLE FLAKVNGTTP 300
CAFPTHYEEA LKDEEKAGV
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0825--Tumor antigen
KW-0833--Ubl conjugation pathway
Interpro

IPR021072--MAGE_N
IPR030084--MAGEB2
IPR002190--MHD_dom
PROSITE

PS50838--MAGE
Pfam

PF01454--MAGE
PF12440--MAGE_N
Gene Ontology