dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000958
Uniprot Accession O15417; TNC18_HUMAN; A8MX41; Q96JH1; Q96K91;
Genbank Protein ID NP_001073964.2;
Genbank Nucleotide ID NM_001080495.2;
Protein Name Trinucleotide repeat-containing gene 18 protein
Protein Synonyms/Alias Long CAG trinucleotide repeat-containing gene 79 protein;
Gene Name TNRC18
Gene Synonyms/Alias CAGL79;KIAA1856;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 122 (View all)
PositionPeptidesSourceReferences ( PMIDs )
41TAGRLPASGLPGPLPPhosphoSitePlus22135298
84PSASSHGSPVPLPSDcurated25850435
185SHAPSARTPGGGHSSdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298
263PRLAERLSPFLAESKdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 19276368; 22115753; 18988627;
269LSPFLAESKTKNAALPhosphoSitePlus;curated22135298; 25850435
333PGPRPCPSPLPPPPAPhosphoSitePlus;curated22135298; 25850435; 25627689
416VLQAPPGSPRPLDRPcurated26074081
611PGGCGKKSPFGGLGTPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 23898821; 23090842; 25849741
660RDPERPESAKAFGREcurated25850435
712VDQERSLSLSNVKGHPhosphoSitePlus;curated22135298; 25627689
991GTYGKAVSPPPSPRAdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 20068231; 20164059; 20363803;
995KAVSPPPSPRASPVAdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 20068231; 20164059; 20363803;
999PPPSPRASPVAALKAdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 20068231; 20164059; 20363803;
1023SKPPAYAYPATPSSHHPRD 918669648; 18988627
1026PAYAYPATPSSHPTScurated20873877
1028YAYPATPSSHPTSPPPhosphoPep 2.0;curated19060867; 25627689; 23090842; 20873877
1029AYPATPSSHPTSPPPPhosphoPep 2.0;curated19060867; 25627689; 20873877
1032ATPSSHPTSPPPASPHPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 18988627; 19060867; 22135298; 25627689; 23898821;
1033TPSSHPTSPPPASPPPhosphoPep 2.0;curated19060867; 25627689; 23898821; 23090842; 20873877
1038PTSPPPASPPPTPGIdbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 19060867; 22135298;
Sequence
(Fasta)		MDGRDFGPQR SVHGPPPPLL SGLAMDSHRV GAATAGRLPA SGLPGPLPPG KYMAGLNLHP 60
HPGEAFLGSF VASGMGPSAS SHGSPVPLPS DLSFRSPTPS NLPMVQLWAA HAHEGFSHLP 120
SGLYPSYLHL NHLEPPSSGS PLLSQLGQPS IFDTQKGQGP GGDGFYLPTA GAPGSLHSHA 180
PSARTPGGGH SSGAPAKGSS SRDGPAKERA GRGGEPPPLF GKKDPRARGE EASGPRGVVD 240
LTQEARAEGR QDRGPPRLAE RLSPFLAESK TKNAALQPSV LTMCNGGAGD VGLPALVAEA 300
GRGGAKEAAR QDEGARLLRR TETLLPGPRP CPSPLPPPPA PPKGPPAPPA ATPAGVYTVF 360
REQGREHRVV APTFVPSVEA FDERPGPIQI ASQARDARAR EREAGRPGVL QAPPGSPRPL 420
DRPEGLREKN SVIRSLKRPP PADAPTVRAT RASPDPRAYV PAKELLKPEA DPRPCERAPR 480
GPAGPAAQQA AKLFGLEPGR PPPTGPEHKW KPFELGNFAA TQMAVLAAQH HHSRAEEEAA 540
VVAASSSKKA YLDPGAVLPR SAATCGRPVA DMHSAAHGSG EASAMQSLIK YSGSFARDAV 600
AVRPGGCGKK SPFGGLGTMK PEPAPTSAGA SRAQARLPHS GGPAAGGGRQ LKRDPERPES 660
AKAFGREGSG AQGEAEVRHP PVGIAVAVAR QKDSGGSGRL GPGLVDQERS LSLSNVKGHG 720
RADEDCVDDR ARHREERLLG ARLDRDQEKL LRESKELADL ARLHPTSCAP NGLNPNLMVT 780
GGPALAGSGR WSADPAAHLA THPWLPRSGN ASMWLAGHPY GLGPPSLHQG MAPAFPPGLG 840
GSLPSAYQFV RDPQSGQLVV IPSDHLPHFA ELMERATVPP LWPALYPPGR SPLHHAQQLQ 900
LFSQQHFLRQ QEFLYLQQQA AQALELQRSA QLVQERLKAQ EHRAEMEEKG SKRGLEAAGK 960
AGLATAGPGL LPRKPPGLAA GPAGTYGKAV SPPPSPRASP VAALKAKVIQ KLEDVSKPPA 1020
YAYPATPSSH PTSPPPASPP PTPGITRKEE APENVVEKKD LELEKEAPSP FQALFSDIPP 1080
RYPFQALPPH YGRPYPFLLQ PTAAADADGL APDVPLPADG PERLALSPED KPIRLSPSKI 1140
TEPLREGPEE EPLAEREVKA EVEDMDEGPT ELPPLESPLP LPAAEAMATP SPAGGCGGGL 1200
LEAQALSATG QSCAEPSECP DFVEGPEPRV DSPGRTEPCT AALDLGVQLT PETLVEAKEE 1260
PVEVPVAVPV VEAVPEEGLA QVAPSESQPT LEMSDCDVPA GEGQCPSLEP QEAVPVLGST 1320
CFLEEASSDQ FLPSLEDPLA GMNALAAAAE LPQARPLPSP GAAGAQALEK LEAAESLVLE 1380
QSFLHGITLL SEIAELELER RSQEMGGAER ALVARPSLES LLAAGSHMLR EVLDGPVVDP 1440
LKNLRLPREL KPNKKYSWMR KKEERMYAMK SSLEDMDALE LDFRMRLAEV QRQYKEKQRE 1500
LVKLQRRRDS EDRREEPHRS LARRGPGRPR KRTHAPSALS PPRKRGKSGH SSGKLSSKSL 1560
LTSDDYELGA GIRKRHKGSE EEHDALIGMG KARGRNQTWD EHEASSDFIS QLKIKKKKMA 1620
SDQEQLASKL DKALSLTKQD KLKSPFKFSD SAGGKSKTSG GCGRYLTPYD SLLGKNRKAL 1680
AKGLGLSLKS SREGKHKRAA KTRKMEVGFK ARGQPKSAHS PFASEVSSYS YNTDSEEDEE 1740
FLKDEWPAQG PSSSKLTPSL LCSMVAKNSK AAGGPKLTKR GLAAPRTLKP KPATSRKQPF 1800
CLLLREAEAR SSFSDSSEES FDQDESSEEE DEEEELEEED EASGGGYRLG ARERALSPGL 1860
EESGLGLLAR FAASALPSPT VGPSLSVVQL EAKQKARKKE ERQSLLGTEF EYTDSESEVK 1920
VRKRSPAGLL RPKKGLGEPG PSLAAPTPGA RGPDPSSPDK AKLAVEKGRK ARKLRGPKEP 1980
GFEAGPEASD DDLWTRRRSE RIFLHDASAA APAPVSTAPA TKTSRCAKGG PLSPRKDAGR 2040
AKDRKDPRKK KKGKEAGPGA GLPPPRAPAL PSEARAPHAS SLTAAKRSKA KAKGKEVKKE 2100
NRGKGGAVSK LMESMAAEED FEPNQDSSFS EDEHLPRGGA VERPLTPAPR SCIIDKDELK 2160
DGLRVLIPMD DKLLYAGHVQ TVHSPDIYRV VVEGERGNRP HIYCLEQLLQ EAIIDVRPAS 2220
TRFLPQGTRI AAYWSQQYRC LYPGTVVRGL LDLEDDGDLI TVEFDDGDTG RIPLSHIRLL 2280
PPDYKIQCAE PSPALLVPSA KRRSRKTSKD TGEGKDGGTA GSEEPGAKAR GRGRKPSAKA 2340
KGDRAATLEE GNPTDEVPST PLALEPSSTP GSKKSPPEPV DKRAKAPKAR PAPPQPSPAP 2400
PAFTSCPAPE PFAELPAPAT SLAPAPLITM PATRPKPKKA RAAEESGAKG PRRPGEEAEL 2460
LVKLDHEGVT SPKSKKAKEA LLLREDPGAG GWQEPKSLLS LGSYPPAAGS SEPKAPWPKA 2520
TDGDLAQEPG PGLTFEDSGN PKSPDKAQAE QDGAEESESS SSSSSGSSSS SSSSSSSGSE 2580
TEGEEEGDKN GDGGCGTGGR NCSAASSRAA SPASSSSSSS SSSSSSSSSS SSSSSSSSSS 2640
SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS STTDEDSSCS SDDEAAPAPT AGPSAQAALP 2700
TKATKQAGKA RPSAHSPGKK TPAPQPQAPP PQPTQPLQPK AQAGAKSRPK KREGVHLPTT 2760
KELAKRQRLP SVENRPKIAA FLPARQLWKW FGKPTQRRGM KGKARKLFYK AIVRGKEMIR 2820
IGDCAVFLSA GRPNLPYIGR IQSMWESWGN NMVVRVKWFY HPEETSPGKQ FHQGQHWDQK 2880
SSRSLPAALR VSSQRKDFME RALYQSSHVD ENDVQTVSHK CLVVGLEQYE QMLKTKKYQD 2940
SEGLYYLAGT YEPTTGMIFS TDGVPVLC 2969
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR001025--BAH_dom
PROSITE

PS51038--BAH
Pfam

PF01426--BAH
Gene Ontology

GO:0000785--C:chromatin
GO:0005677--C:chromatin silencing complex
GO:0005737--C:cytoplasm
GO:0005739--C:mitochondrion
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0006342--P:chromatin silencing
GO:0031507--P:heterochromatin assembly