dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000954
Uniprot Accession O15400; STX7_HUMAN; E1P579; Q5SZW2; Q96ES9;
Genbank Protein ID NP_003560.2; XP_011534480.1;
Genbank Nucleotide ID NM_003569.2; XM_011536178.1;
Protein Name Syntaxin-7
Protein Synonyms/Alias
Gene Name STX7
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
Phosphorylation Sites
 dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
2------MSYTPGVGGdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18578522; 16381945; 23193290; 18988627; 22135298; 25850435
3-----MSYTPGVGGDdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated19413330; 16381945; 23193290; 18988627; 22135298; 25627689;
4----MSYTPGVGGDPdbPTM 3.0;PhosphoSitePlus;curated18578522; 16381945; 23193290; 22135298; 25627689; 23186163
35CSVEIQRTLNQLGTPPHOSIDA21081558
41RTLNQLGTPQDSPELPhosphoSitePlus;curated22135298; 25627689; 23186163
45QLGTPQDSPELRQQLPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 25850435; 25627689; 22199227; 24961811
75KYIKEFGSLPTTPSEPhosphoSitePlus;curated22135298; 25850435; 25627689
78KEFGSLPTTPSEQRQdbPTM 3.0;Phospho.ELM 9.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 19690332; 22135298; 23403867;
79EFGSLPTTPSEQRQRdbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated19690332; 16381945; 23193290; 18578522; 18669648; 19664994;
81GSLPTTPSEQRQRKIdbPTM 3.0;PhosphoSitePlus;curated20886841; 16381945; 23193290; 22135298; 25850435; 25627689
125FVARVRASSRVSGSFdbPTM 3.0;PhosphoSitePlus;curated20736484; 16381945; 23193290; 22135298; 25627689; 23898821;
126VARVRASSRVSGSFPdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18578522; 20363803; 20736484; 16381945; 23193290; 18988627;
129VRASSRVSGSFPEDSdbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 20166139; 20363803; 20736484;
131ASSRVSGSFPEDSSKdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20166139; 20363803; 20736484; 16381945; 23193290; 18988627;
136SGSFPEDSSKERNLVcurated23917254
144SKERNLVSWESQTQPPhosphoSitePlus22135298
149LVSWESQTQPQVQVQdbPTM 3.0;PhosphoSitePlus;curated18578522; 16381945; 23193290; 22135298; 22817900
205EQGDVIDSIEANVENPhosphoSitePlus;UniProt;curated22135298; 24275569; 25850435
Sequence
(Fasta)		MSYTPGVGGD PAQLAQRISS NIQKITQCSV EIQRTLNQLG TPQDSPELRQ QLQQKQQYTN 60
QLAKETDKYI KEFGSLPTTP SEQRQRKIQK DRLVAEFTTS LTNFQKVQRQ AAEREKEFVA 120
RVRASSRVSG SFPEDSSKER NLVSWESQTQ PQVQVQDEEI TEDDLRLIHE RESSIRQLEA 180
DIMDINEIFK DLGMMIHEQG DVIDSIEANV ENAEVHVQQA NQQLSRAADY QRKSRKTLCI 240
IILILVIGVA IISLIIWGLN H 262
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0967--Endosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR006012--Syntaxin/epimorphin_CS
IPR006011--Syntaxin_N
IPR010989--t-SNARE
IPR000727--T_SNARE_dom
PROSITE

PS00914--SYNTAXIN
PS50192--T_SNARE
Pfam

PF05739--SNARE
Gene Ontology

GO:0042582--C:azurophil granule
GO:0005769--C:early endosome
GO:0031901--C:early endosome membrane
GO:0030139--C:endocytic vesicle
GO:0012505--C:endomembrane system
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0016021--C:integral component of membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005770--C:late endosome
GO:0005765--C:lysosomal membrane
GO:0005764--C:lysosome
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0055037--C:recycling endosome
GO:0031201--C:SNARE complex
GO:0070820--C:tertiary granule
GO:0031982--C:vesicle
GO:0019869--F:chloride channel inhibitor activity
GO:0005484--F:SNAP receptor activity
GO:0000149--F:SNARE binding
GO:0019905--F:syntaxin binding
GO:0006886--P:intracellular protein transport
GO:0070925--P:organelle assembly
GO:0051640--P:organelle localization
GO:1902685--P:positive regulation of receptor localization to synapse
GO:0001916--P:positive regulation of T cell mediated cytotoxicity
GO:1903076--P:regulation of protein localization to plasma membrane
GO:0048278--P:vesicle docking
GO:0006906--P:vesicle fusion