dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000951
Uniprot Accession O15394; NCAM2_HUMAN; A8MQ06; B7Z841; Q7Z7F2;
Genbank Protein ID NP_004531.2;
Genbank Nucleotide ID NM_004540.3;
Protein Name Neural cell adhesion molecule 2
Protein Synonyms/Alias
Gene Name NCAM2
Gene Synonyms/Alias NCAM21;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Phosphorylation Sites
 dbPAF PTMs: 15
PositionPeptidesSourceReferences ( PMIDs )
91NIEDAGIYRCQATDAPhosphoSitePlus22135298
116LEIYQKLTFREVVSPdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20058876; 16381945; 23193290; 18988627; 22135298; 22817900
122LTFREVVSPQEFKQGdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20058876; 16381945; 23193290; 18988627; 22135298; 22817900
451KNTTNLKTYSTGRKMPhosphoSitePlus22135298
453TTNLKTYSTGRKMILPhosphoSitePlus22135298
630ILEYIVKYRSKDKEDcurated26074081
632EYIVKYRSKDKEDQWcurated26074081
760LEEGKAAYLKDGSKEPhosphoSitePlus22135298
765AAYLKDGSKEPIVEMcurated25219547; 25849741
774EPIVEMRTEDERVTNcurated25849741
780RTEDERVTNHEDGSPcurated25849741
786VTNHEDGSPVNEPNEdbPTM 3.0;PhosphoSitePlus;curated18510355; 20886841; 16381945; 23193290; 22135298; 25850435;
794PVNEPNETTPLTEPEdbPTM 3.0;PhosphoSitePlus;curated18510355; 16381945; 23193290; 22135298; 22817900
795VNEPNETTPLTEPEKdbPTM 3.0;HPRD 9;SysPTM 2.0;curated18510355; 16381945; 23193290; 18988627; 19366988; 25849741
824ETIEIKVSNDIIQSKcurated25849741
Sequence
(Fasta)		MSLLLSFYLL GLLVSSGQAL LQVTISLSKV ELSVGESKFF TCTAIGEPES IDWYNPQGEK 60
IISTQRVVVQ KEGVRSRLTI YNANIEDAGI YRCQATDAKG QTQEATVVLE IYQKLTFREV 120
VSPQEFKQGE DAEVVCRVSS SPAPAVSWLY HNEEVTTISD NRFAMLANNN LQILNINKSD 180
EGIYRCEGRV EARGEIDFRD IIVIVNVPPA ISMPQKSFNA TAERGEEMTF SCRASGSPEP 240
AISWFRNGKL IEENEKYILK GSNTELTVRN IINSDGGPYV CRATNKAGED EKQAFLQVFV 300
QPHIIQLKNE TTYENGQVTL VCDAEGEPIP EITWKRAVDG FTFTEGDKSL DGRIEVKGQH 360
GSSSLHIKDV KLSDSGRYDC EAASRIGGHQ KSMYLDIEYA PKFISNQTIY YSWEGNPINI 420
SCDVKSNPPA SIHWRRDKLV LPAKNTTNLK TYSTGRKMIL EIAPTSDNDF GRYNCTATNH 480
IGTRFQEYIL ALADVPSSPY GVKIIELSQT TAKVSFNKPD SHGGVPIHHY QVDVKEVASE 540
IWKIVRSHGV QTMVVLNNLE PNTTYEIRVA AVNGKGQGDY SKIEIFQTLP VREPSPPSIH 600
GQPSSGKSFK LSITKQDDGG APILEYIVKY RSKDKEDQWL EKKVQGNKDH IILEHLQWTM 660
GYEVQITAAN RLGYSEPTVY EFSMPPKPNI IKDTLFNGLG LGAVIGLGVA ALLLILVVTD 720
VSCFFIRQCG LLMCITRRMC GKKSGSSGKS KELEEGKAAY LKDGSKEPIV EMRTEDERVT 780
NHEDGSPVNE PNETTPLTEP EKLPLKEEDG KEALNPETIE IKVSNDIIQS KEDDSKA 838
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0130--Cell adhesion
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0393--Immunoglobulin domain
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR003961--FN3_dom
IPR007110--Ig-like_dom
IPR013783--Ig-like_fold
IPR013098--Ig_I-set
IPR003598--Ig_sub2
IPR009138--Neural_cell_adh
PROSITE

PS50853--FN3
PS50835--IG_LIKE
Pfam

PF00041--fn3
PF07679--I-set
Gene Ontology

GO:0030424--C:axon
GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0007158--P:neuron cell-cell adhesion