dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000948
Uniprot Accession O15391; TYY2_HUMAN; B2RP10; Q6Q1S4;
Genbank Protein ID NP_996806.2;
Genbank Nucleotide ID NM_206923.3;
Protein Name Transcription factor YY2
Protein Synonyms/Alias Yin and yang 2;YY-2;Zinc finger protein 631;
Gene Name YY2
Gene Synonyms/Alias ZNF631;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
130LSASAASTSTSTQSRPhosphoSitePlus22135298
152PSGKSATSTEANPAGPhosphoSitePlus22135298
160TEANPAGSSSSLGTRPhosphoSitePlus22135298
161EANPAGSSSSLGTRKPhosphoSitePlus22135298
163NPAGSSSSLGTRKWEPhosphoSitePlus22135298
306RRHQLVHTGEKPFQCPhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;curated19060867; 22135298; 18669648; 19366988; 25627689; 23186163;
323EGCGKRFSLDFNLRTHPRD 9;PhosphoSitePlus;curated20068231; 18988627; 22135298; 23898821; 26074081
330SLDFNLRTHLRIHTGcurated26074081
Sequence
(Fasta)		MASNEDFSIT QDLEIPADIV ELHDINVEPL PMEDIPTESV QYEDVDGNWI YGGHNHPPLM 60
VLQPLFTNTG YGDHDQEMLM LQTQEEVVGY CDSDNQLGND LEDQLALPDS IEDEHFQMTL 120
ASLSASAAST STSTQSRSKK PSKKPSGKSA TSTEANPAGS SSSLGTRKWE QKQMQVKTLE 180
GEFSVTMWSP NDNNDQGAVG EGQAENPPDY SEYLKGKKLP PGGLPGIDLS DPKQLAEFTK 240
VKPKRSKGEP PKTVPCSYSG CEKMFRDYAA MRKHLHIHGP RVHVCAECGK AFLESSKLRR 300
HQLVHTGEKP FQCTFEGCGK RFSLDFNLRT HLRIHTGDKP FVCPFDVCNR KFAQSTNLKT 360
HILTHVKTKN NP 373
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR017114--TF_Yin_yang
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd
PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated