dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000939
Uniprot Accession O15370; SOX12_HUMAN; Q5D038; Q9NUD4;
Genbank Protein ID NP_008874.2;
Genbank Nucleotide ID NM_006943.3;
Protein Name Transcription factor SOX-12
Protein Synonyms/Alias Protein SOX-22;
Gene Name SOX12
Gene Synonyms/Alias SOX22;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Binds to the sequence 5'-AACAAT-3'.
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
104RLKHMADYPDYKYRPPhosphoSitePlus;curated22135298; 22817900
107HMADYPDYKYRPRKKPhosphoSitePlus;curated22135298; 22817900
134PGGSGGGSRLKPGPQcurated24732914
181LEVRLVETPGRELWRPhosphoSitePlus22135298
Sequence
(Fasta)		MVQQRGARAK RDGGPPPPGP GPAEEGAREP GWCKTPSGHI KRPMNAFMVW SQHERRKIMD 60
QWPDMHNAEI SKRLGRRWQL LQDSEKIPFV REAERLRLKH MADYPDYKYR PRKKSKGAPA 120
KARPRPPGGS GGGSRLKPGP QLPGRGGRRA AGGPLGGGAA APEDDDEDDD EELLEVRLVE 180
TPGRELWRMV PAGRAARGQA ERAQGPSGEG AAAAAAASPT PSEDEEPEEE EEEAAAAEEG 240
EEETVASGEE SLGFLSRLPP GPAGLDCSAL DRDPDLQPPS GTSHFEFPDY CTPEVTEMIA 300
GDWRPSSIAD LVFTY 316
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR009071--HMG_box_dom
IPR031267--SOX-12
PROSITE

PS50118--HMG_BOX_2
Pfam

PF00505--HMG_box
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0032993--C:protein-DNA complex
GO:0003677--F:DNA binding
GO:0001105--F:RNA polymerase II transcription coactivator activity
GO:0000976--F:transcription regulatory region sequence-specific DNA binding
GO:0001077--F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0045165--P:cell fate commitment
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0065004--P:protein-DNA complex assembly
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0021510--P:spinal cord development