dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000936
Uniprot Accession O15355; PPM1G_HUMAN;
Genbank Protein ID NP_817092.1;
Genbank Nucleotide ID NM_177983.2;
Protein Name Protein phosphatase 1G
Protein Synonyms/Alias Protein phosphatase 1C;Protein phosphatase 2C isoform gamma;PP2C-gamma;Protein phosphatase magnesium-dependent 1 gamma;
Gene Name PPM1G
Gene Synonyms/Alias PPM1C;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 32 (View all)
PositionPeptidesSourceReferences ( PMIDs )
4----MGAYLSQPNTVPhosphoSitePlus22135298
6--MGAYLSQPNTVKCPhosphoSitePlus22135298
10AYLSQPNTVKCSGDGPhosphoSitePlus22135298
122AQIAGRPTEDEDEKEPhosphoSitePlus;curated22135298; 25627689; 23917254; 23186163; 20873877; 24961811
160IEELLTRYGQNCHKGPhosphoSitePlus22135298
173KGPPHSKSGGGTGEEPhosphoSitePlus;curated22135298; 25627689; 25003641
177HSKSGGGTGEEPGSQcurated25627689; 23186163
183GTGEEPGSQGLNGEAdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated17525332; 16381945; 23193290; 18077418; 22424773; 18988627;
195GEAGPEDSTRETPSQdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18077418; 18988627; 22135298;
196EAGPEDSTRETPSQEPhosphoSitePlus;curated22135298; 25627689
199PEDSTRETPSQENGPdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18077418; 16381945; 23193290; 18988627; 22135298; 25627689;
201DSTRETPSQENGPTAdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated21406692; 22424773; 16381945; 23193290; 18077418; 18988627;
207PSQENGPTAKAYTGFPhosphoSitePlus22135298
211NGPTAKAYTGFSSNSPhosphoSitePlus22135298
215AKAYTGFSSNSERGTcurated25627689
216KAYTGFSSNSERGTEPhosphoSitePlus;curated22135298; 25627689; 23186163; 20873877
218YTGFSSNSERGTEAGcurated25627689; 23186163; 20873877
240PTGEAGPSCSSASDKcurated25627689
242GEAGPSCSSASDKLPcurated25627689
243EAGPSCSSASDKLPRcurated25627689
Sequence
(Fasta)
MGAYLSQPNT VKCSGDGVGA PRLPLPYGFS AMQGWRVSME DAHNCIPELD SETAMFSVYD 60
GHGGEEVALY CAKYLPDIIK DQKAYKEGKL QKALEDAFLA IDAKLTTEEV IKELAQIAGR 120
PTEDEDEKEK VADEDDVDNE EAALLHEEAT MTIEELLTRY GQNCHKGPPH SKSGGGTGEE 180
PGSQGLNGEA GPEDSTRETP SQENGPTAKA YTGFSSNSER GTEAGQVGEP GIPTGEAGPS 240
CSSASDKLPR VAKSKFFEDS EDESDEAEEE EEDSEECSEE EDGYSSEEAE NEEDEDDTEE 300
AEEDDEEEEE EMMVPGMEGK EEPGSDSGTT AVVALIRGKQ LIVANAGDSR CVVSEAGKAL 360
DMSYDHKPED EVELARIKNA GGKVTMDGRV NGGLNLSRAI GDHFYKRNKN LPPEEQMISA 420
LPDIKVLTLT DDHEFMVIAC DGIWNVMSSQ EVVDFIQSKI SQRDENGELR LLSSIVEELL 480
DQCLAPDTSG DGTGCDNMTC IIICFKPRNT AELQPESGKR KLEEVLSTEG AEENGNSDKK 540
KKAKRD 547
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0449--Lipoprotein
KW-0460--Magnesium
KW-0464--Manganese
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-0597--Phosphoprotein
KW-0904--Protein phosphatase
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR015655--PP2C
IPR000222--PP2C_BS
IPR001932--PPM-type_phosphatase_dom

PROSITE

PS01032--PPM_1
PS51746--PPM_2

Pfam

PF00481--PP2C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0007050--P:cell cycle arrest
GO:0035970--P:peptidyl-threonine dephosphorylation
GO:0006470--P:protein dephosphorylation