Tag |
Content |
dbPAF ID |
dbPAF-0000919 |
Uniprot Accession |
O15273; TELT_HUMAN; Q96L27; |
Genbank Protein ID |
NP_003664.1; |
Genbank Nucleotide ID |
NM_003673.3; |
Protein Name |
Telethonin |
Protein Synonyms/Alias |
Titin cap protein; |
Gene Name |
TCAP |
Gene Synonyms/Alias |
|
Organism |
Homo sapiens(Human) |
NCBI Taxa ID |
9606 |
Functional Description (View all) |
Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.Functional Description
Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at the sarcomeric Z-disk.
|
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence (Fasta) | MATSELSCEV SEENCERREA FWAEWKDLTL STRPEEGCSL HEEDTQRHET YHQQGQCQVL 60 VQRSPWLMMR MGILGRGLQE YQLPYQRVLP LPIFTPAKMG ATKEEREDTP IQLQELLALE 120 TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM SQEAQRG
168Fasta Sequence
>O15273|TCAP|Homo sapiens(Human) MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
|
Keyword |
KW-0002--3D-structure KW-0122--Cardiomyopathy KW-0181--Complete proteome KW-0963--Cytoplasm KW-0225--Disease mutation KW-0947--Limb-girdle muscular dystrophy KW-0597--Phosphoprotein KW-0621--Polymorphism KW-1185--Reference proteome
|
Interpro |
IPR015667--Telethonin IPR023111--Titin-like_domain
|
PROSITE |
|
Pfam |
PF09470--Telethonin
|
Gene Ontology |
GO:0005829--C:cytosol GO:0031674--C:I band GO:0030018--C:Z disc GO:0036122--F:BMP binding GO:0051373--F:FATZ binding GO:0044325--F:ion channel binding GO:0030674--F:protein binding, bridging GO:0008307--F:structural constituent of muscle GO:0031432--F:titin binding GO:0070080--F:titin Z domain binding GO:0007512--P:adult heart development GO:0060048--P:cardiac muscle contraction GO:0048739--P:cardiac muscle fiber development GO:0003300--P:cardiac muscle hypertrophy GO:0014898--P:cardiac muscle hypertrophy in response to stress GO:0055008--P:cardiac muscle tissue morphogenesis GO:0055003--P:cardiac myofibril assembly GO:0050982--P:detection of mechanical stimulus GO:0035995--P:detection of muscle stretch GO:0030049--P:muscle filament sliding GO:0030916--P:otic vesicle formation GO:0006461--P:protein complex assembly GO:0035994--P:response to muscle stretch GO:0045214--P:sarcomere organization GO:0048769--P:sarcomerogenesis GO:0003009--P:skeletal muscle contraction GO:0030241--P:skeletal muscle myosin thick filament assembly GO:0030240--P:skeletal muscle thin filament assembly GO:0001756--P:somitogenesis
|