dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000916
Uniprot Accession O15266; SHOX_HUMAN; O00412; O00413; O15267;
Genbank Protein ID NP_000442.1; NP_006874.1;
Genbank Nucleotide ID NM_000451.3; NM_006883.2;
Protein Name Short stature homeobox protein
Protein Synonyms/Alias Pseudoautosomal homeobox-containing osteogenic protein;Short stature homeobox-containing protein;
Gene Name SHOX
Gene Synonyms/Alias PHOG;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Controls fundamental aspects of growth and development.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
5---MEELTAFVSKSFPhosphoSitePlus;curated22135298; 26074081
9EELTAFVSKSFDQKSPhosphoSitePlus22135298
46LESGLARSRELGTSDdbPTM 3.0;PhosphoSitePlus;curated22115753; 16381945; 23193290; 22135298; 24260401
106EKREDVKSEDEDGQTdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated16325853; 16381945; 23193290; 18988627; 22135298; 22817900
120TKLKQRRSRTNFTLEPhosphoSitePlus;curated22135298; 22817900
125RRSRTNFTLEQLNELPhosphoSitePlus;curated22135298; 22817900
141RLFDETHYPDAFMREPhosphoSitePlus;curated22135298; 22817900
Sequence
(Fasta)		MEELTAFVSK SFDQKSKDGN GGGGGGGGKK DSITYREVLE SGLARSRELG TSDSSLQDIT 60
EGGGHCPVHL FKDHVDNDKE KLKEFGTARV AEGIYECKEK REDVKSEDED GQTKLKQRRS 120
RTNFTLEQLN ELERLFDETH YPDAFMREEL SQRLGLSEAR VQVWFQNRRA KCRKQENQMH 180
KGVILGTANH LDACRVAPYV NMGALRMPFQ QVQAQLQLEG VAHAHPHLHP HLAAHAPYLM 240
FPPPPFGLPI ASLAESASAA AVVAAAAKSN SKNSSIADLR LKARKHAEAL GL 293
Keyword

KW-0010--Activator
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0225--Disease mutation
KW-0238--DNA-binding
KW-0242--Dwarfism
KW-0371--Homeobox
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR017970--Homeobox_CS
IPR001356--Homeobox_dom
IPR009057--Homeodomain-like
IPR000047--HTH_motif
IPR003654--OAR_dom
PROSITE

PS00027--HOMEOBOX_1
PS50071--HOMEOBOX_2
PS50803--OAR
Pfam

PF00046--Homeobox
PF03826--OAR
Gene Ontology

GO:0005634--C:nucleus
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0001501--P:skeletal system development
GO:0006366--P:transcription from RNA polymerase II promoter