| Tag |
Content |
| dbPAF ID |
dbPAF-0000909 |
| Uniprot Accession |
O15254; ACOX3_HUMAN; Q96AJ8;
|
| Genbank Protein ID |
NP_001095137.1; NP_003492.2; XP_005248068.1; XP_005248070.1; XP_011511867.1;
|
| Genbank Nucleotide ID |
NM_001101667.1; NM_003501.2; XM_005248011.3; XM_005248013.3; XM_011513565.1;
|
| Protein Name |
Peroxisomal acyl-coenzyme A oxidase 3 |
| Protein Synonyms/Alias |
Branched-chain acyl-CoA oxidase;BRCACox;Pristanoyl-CoA oxidase; |
| Gene Name |
ACOX3 |
| Gene Synonyms/Alias |
BRCOX;PRCOX; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
Oxidizes the CoA-esters of 2-methyl-branched fatty acids.Functional Description
Oxidizes the CoA-esters of 2-methyl-branched fatty acids. |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MASTVEGGDT ALLPEFPRGP LDAYRARASF SWKELALFTE GEGMLRFKKT IFSALENDPL 60
FARSPGADLS LEKYRELNFL RCKRIFEYDF LSVEDMFKSP LKVPALIQCL GMYDSSLAAK 120
YLLHSLVFGS AVYSSGSERH LTYIQKIFRM EIFGCFALTE LSHGSNTKAI RTTAHYDPAT 180
EEFIIHSPDF EAAKFWVGNM GKTATHAVVF AKLCVPGDQC HGLHPFIVQI RDPKTLLPMP 240
GVMVGDIGKK LGQNGLDNGF AMFHKVRVPR QSLLNRMGDV TPEGTYVSPF KDVRQRFGAS 300
LGSLSSGRVS IVSLAILNLK LAVAIALRFS ATRRQFGPTE EEEIPVLEYP MQQWRLLPYL 360
AAVYALDHFS KSLFLDLVEL QRGLASGDRS ARQAELGREI HALASASKPL ASWTTQQGIQ 420
ECREACGGHG YLAMNRLGVL RDDNDPNCTY EGDNNILLQQ TSNYLLGLLA HQVHDGACFR 480
SPLKSVDFLD AYPGILDQKF EVSSVADCLD SAVALAAYKW LVCYLLRETY QKLNQEKRSG 540
SSDFEARNKC QVSHGRPLAL AFVELTVVQR FHEHVHQPSV PPSLRAVLGR LSALYALWSL 600
SRHAALLYRG GYFSGEQAGE VLESAVLALC SQLKDDAVAL VDVIAPPDFV LDSPIGRADG 660
ELYKNLWGAV LQESKVLERA SWWPEFSVNK PVIGSLKSKL
701Fasta Sequence
>O15254|ACOX3|Homo sapiens(Human)
MASTVEGGDTALLPEFPRGPLDAYRARASFSWKELALFTEGEGMLRFKKTIFSALENDPLFARSPGADLSLEKYRELNFLRCKRIFEYDFLSVEDMFKSPLKVPALIQCLGMYDSSLAAKYLLHSLVFGSAVYSSGSERHLTYIQKIFRMEIFGCFALTELSHGSNTKAIRTTAHYDPATEEFIIHSPDFEAAKFWVGNMGKTATHAVVFAKLCVPGDQCHGLHPFIVQIRDPKTLLPMPGVMVGDIGKKLGQNGLDNGFAMFHKVRVPRQSLLNRMGDVTPEGTYVSPFKDVRQRFGASLGSLSSGRVSIVSLAILNLKLAVAIALRFSATRRQFGPTEEEEIPVLEYPMQQWRLLPYLAAVYALDHFSKSLFLDLVELQRGLASGDRSARQAELGREIHALASASKPLASWTTQQGIQECREACGGHGYLAMNRLGVLRDDNDPNCTYEGDNNILLQQTSNYLLGLLAHQVHDGACFRSPLKSVDFLDAYPGILDQKFEVSSVADCLDSAVALAAYKWLVCYLLRETYQKLNQEKRSGSSDFEARNKCQVSHGRPLALAFVELTVVQRFHEHVHQPSVPPSLRAVLGRLSALYALWSLSRHAALLYRGGYFSGEQAGEVLESAVLALCSQLKDDAVALVDVIAPPDFVLDSPIGRADGELYKNLWGAVLQESKVLERASWWPEFSVNKPVIGSLKSKL
|
| Keyword |
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0274--FAD
KW-0276--Fatty acid metabolism
KW-0285--Flavoprotein
KW-0443--Lipid metabolism
KW-0560--Oxidoreductase
KW-0576--Peroxisome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
|
| Interpro |
IPR006091--Acyl-CoA_Oxase/DH_cen-dom
IPR012258--Acyl-CoA_oxidase
IPR002655--Acyl-CoA_oxidase_C
IPR009075--AcylCo_DH/oxidase_C
IPR009100--AcylCoA_DH/oxidase_NM_dom
|
| PROSITE |
|
| Pfam |
PF01756--ACOX
PF00441--Acyl-CoA_dh_1
PF02770--Acyl-CoA_dh_M
|
| Gene Ontology |
GO:0016020--C:membrane
GO:0005739--C:mitochondrion
GO:0005782--C:peroxisomal matrix
GO:0005777--C:peroxisome
GO:0003995--F:acyl-CoA dehydrogenase activity
GO:0009055--F:electron carrier activity
GO:0000062--F:fatty-acyl-CoA binding
GO:0050660--F:flavin adenine dinucleotide binding
GO:0052890--F:oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
GO:0016402--F:pristanoyl-CoA oxidase activity
GO:0005102--F:receptor binding
GO:0044255--P:cellular lipid metabolic process
GO:0033539--P:fatty acid beta-oxidation using acyl-CoA dehydrogenase
GO:0033540--P:fatty acid beta-oxidation using acyl-CoA oxidase
GO:0055088--P:lipid homeostasis
GO:0044281--P:small molecule metabolic process
|
