dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000905
Uniprot Accession O15240; VGF_HUMAN; Q9UDW8;
Genbank Protein ID NP_003369.2; XP_005250618.1; XP_011514850.1; XP_011514851.1;
Genbank Nucleotide ID NM_003378.3; XM_005250561.3; XM_011516548.1; XM_011516549.1;
Protein Name Neurosecretory protein VGF
Protein Synonyms/Alias
Gene Name VGF
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
199LTRVNLESPGPERVWcurated25262027
238FQARMPDSGPLPETHcurated25850435
420AGAEDKRSQEETPGHPhosphoSitePlus;curated22135298; 25850435; 22798277; 25849741; 24961811
424DKRSQEETPGHRRKEPhosphoSitePlus22135298
Sequence
(Fasta)
MKALRLSASA LFCLLLINGL GAAPPGRPEA QPPPLSSEHK EPVAGDAVPG PKDGSAPEVR 60
GARNSEPQDE GELFQGVDPR ALAAVLLQAL DRPASPPAPS GSQQGPEEEA AEALLTETVR 120
SQTHSLPAPE SPEPAAPPRP QTPENGPEAS DPSEELEALA SLLQELRDFS PSSAKRQQET 180
AAAETETRTH TLTRVNLESP GPERVWRASW GEFQARVPER APLPPPAPSQ FQARMPDSGP 240
LPETHKFGEG VSSPKTHLGE ALAPLSKAYQ GVAAPFPKAR RPESALLGGS EAGERLLQQG 300
LAQVEAGRRQ AEATRQAAAQ EERLADLASD LLLQYLLQGG ARQRGLGGRG LQEAAEERES 360
AREEEEAEQE RRGGEERVGE EDEEAAEAEA EAEEAERARQ NALLFAEEED GEAGAEDKRS 420
QEETPGHRRK EAEGTEEGGE EEDDEEMDPQ TIDSLIELST KLHLPADDVV SIIEEVEEKR 480
KRKKNAPPEP VPPPRAAPAP THVRSPQPPP PAPAPARDEL PDWNEVLPPW DREEDEVYPP 540
GPYHPFPNYI RPRTLQPPSA LRRRHYHHAL PPSRHYPGRE AQARRAQEEA EAEERRLQEQ 600
EELENYIEHV LLRRP 616
Keyword

KW-0027--Amidation
KW-0044--Antibiotic
KW-0929--Antimicrobial
KW-0165--Cleavage on pair of basic residues
KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0903--Direct protein sequencing
KW-0339--Growth factor
KW-0597--Phosphoprotein
KW-0873--Pyrrolidone carboxylic acid
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal

Interpro

IPR026128--VGF

PROSITE
Pfam
Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005615--C:extracellular space
GO:0043231--C:intracellular membrane-bounded organelle
GO:0030133--C:transport vesicle
GO:0005179--F:hormone activity
GO:0033500--P:carbohydrate homeostasis
GO:0042742--P:defense response to bacterium
GO:0006091--P:generation of precursor metabolites and energy
GO:0042593--P:glucose homeostasis
GO:0030073--P:insulin secretion
GO:0001541--P:ovarian follicle development
GO:0048167--P:regulation of synaptic plasticity
GO:0051591--P:response to cAMP
GO:0009409--P:response to cold
GO:0002021--P:response to dietary excess
GO:0032868--P:response to insulin
GO:0019953--P:sexual reproduction