dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000889
Uniprot Accession O15204; ADEC1_HUMAN; B7ZAK5;
Genbank Protein ID NP_001138743.1; NP_001138744.1; NP_055294.1;
Genbank Nucleotide ID NM_001145271.1; NM_001145272.1; NM_014479.3;
Protein Name ADAM DEC1
Protein Synonyms/Alias A disintegrin and metalloproteinase domain-like protein decysin-1;ADAM-like protein decysin-1;
Gene Name ADAMDEC1
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May play an important role in the control of the immune response and during pregnancy.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
72KHGKEERYEPEVQYQPhosphoSitePlus22135298
Sequence
(Fasta)
MLRGISQLPA VATMSWVLLP VLWLIVQTQA IAIKQTPELT LHEIVCPKKL HILHKREIKN 60
NQTEKHGKEE RYEPEVQYQM ILNGEEIILS LQKTKHLLGP DYTETLYSPR GEEITTKPEN 120
MEHCYYKGNI LNEKNSVASI STCDGLRGYF THHHQRYQIK PLKSTDEKEH AVFTSNQEEQ 180
DPANHTCGVK STDGKQGPIR ISRSLKSPEK EDFLRAQKYI DLYLVLDNAF YKNYNENLTL 240
IRSFVFDVMN LLNVIYNTID VQVALVGMEI WSDGDKIKVV PSASTTFDNF LRWHSSNLGK 300
KIHDHAQLLS GISFNNRRVG LAASNSLCSP SSVAVIEAKK KNNVALVGVM SHELGHVLGM 360
PDVPFNTKCP SGSCVMNQYL SSKFPKDFST SCRAHFERYL LSQKPKCLLQ APIPTNIMTT 420
PVCGNHLLEV GEDCDCGSPK ECTNLCCEAL TCKLKPGTDC GGDAPNHTTE 471
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0325--Glycoprotein
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0621--Polymorphism
KW-0645--Protease
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0862--Zinc
KW-0865--Zymogen

Interpro

IPR001762--Disintegrin_dom
IPR024079--MetalloPept_cat_dom
IPR001590--Peptidase_M12B
IPR002870--Peptidase_M12B_N

PROSITE

PS50215--ADAM_MEPRO
PS50214--DISINTEGRIN_2
PS00142--ZINC_PROTEASE

Pfam

PF00200--Disintegrin
PF01562--Pep_M12B_propep
PF01421--Reprolysin

Gene Ontology

GO:0005576--C:extracellular region
GO:0004222--F:metalloendopeptidase activity
GO:0008270--F:zinc ion binding
GO:0006955--P:immune response
GO:0007162--P:negative regulation of cell adhesion