dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000886
Uniprot Accession O15195; VILL_HUMAN; A8MZP1; Q9BT80; Q9BWH7;
Genbank Protein ID NP_056957.3; XP_005265248.1; XP_005265249.1; XP_006713247.1; XP_011532072.1;
Genbank Nucleotide ID NM_015873.3; XM_005265191.2; XM_005265192.3; XM_006713184.2; XM_011533770.1;
Protein Name Villin-like protein
Protein Synonyms/Alias
Gene Name VILL
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Possible tumor suppressor.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
62GASSDLHYWVGKQAGPhosphoSitePlus22135298
122YRKGGLASDLKHVETPhosphoSitePlus22135298
294DQGGFKIYVWQGRMSPhosphoSitePlus22135298
301YVWQGRMSSLQERKAPhosphoSitePlus22135298
504GHHGKGQSASTTRLFPhosphoSitePlus22135298
762ALQALKGSQDSSENDPhosphoSitePlus22135298
773SENDLVRSPKSAGSRcurated23898821
821DPARREFYLSDSDFQPhosphoSitePlus22135298
839GKSKEEFYSMATWRQPhosphoSitePlus22135298
Sequence
(Fasta)		MDISKGLPGM QGGLHIWISE NRKMVPVPEG AYGNFFEEHC YVILHVPQSP KATQGASSDL 60
HYWVGKQAGA EAQGAAEAFQ QRLQDELGGQ TVLHREAQGH ESDCFCSYFR PGIIYRKGGL 120
ASDLKHVETN LFNIQRLLHI KGRKHVSATE VELSWNSFNK GDIFLLDLGK MMIQWNGPKT 180
SISEKARGLA LTYSLRDRER GGGRAQIGVV DDEAKAPDLM QIMEAVLGRR VGSLRAATPS 240
KDINQLQKAN VRLYHVYEKG KDLVVLELAT PPLTQDLLQE EDFYILDQGG FKIYVWQGRM 300
SSLQERKAAF SRAVGFIQAK GYPTYTNVEV VNDGAESAAF KQLFRTWSEK RRRNQKLGGR 360
DKSIHVKLDV GKLHTQPKLA AQLRMVDDGS GKVEVWCIQD LHRQPVDPKR HGQLCAGNCY 420
LVLYTYQRLG RVQYILYLWQ GHQATADEIE ALNSNAEELD VMYGGVLVQE HVTMGSEPPH 480
FLAIFQGQLV IFQERAGHHG KGQSASTTRL FQVQGTDSHN TRTMEVPARA SSLNSSDIFL 540
LVTASVCYLW FGKGCNGDQR EMARVVVTVI SRKNEETVLE GQEPPHFWEA LGGRAPYPSN 600
KRLPEEVPSF QPRLFECSSH MGCLVLAEVG FFSQEDLDKY DIMLLDTWQE IFLWLGEAAS 660
EWKEAVAWGQ EYLKTHPAGR SPATPIVLVK QGHEPPTFIG WFFTWDPYKW TSHPSHKEVV 720
DGSPAAASTI SEITAEVNNL RLSRWPGNGR AGAVALQALK GSQDSSENDL VRSPKSAGSR 780
TSSSVSSTSA TINGGLRREQ LMHQAVEDLP EGVDPARREF YLSDSDFQDI FGKSKEEFYS 840
MATWRQRQEK KQLGFF 857
Keyword

KW-0117--Actin capping
KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-0106--Calcium
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR029006--ADF-H/Gelsolin-like_dom
IPR007123--Gelsolin-like_dom
IPR015626--Villin-like
IPR007122--Villin/Gelsolin
IPR003128--Villin_headpiece
PROSITE

PS51089--HP
Pfam

PF00626--Gelsolin
PF02209--VHP
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005200--F:structural constituent of cytoskeleton
GO:0051693--P:actin filament capping
GO:0007010--P:cytoskeleton organization