dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000882
Uniprot Accession O15173; PGRC2_HUMAN; Q569H1;
Genbank Protein ID NP_006311.2;
Genbank Nucleotide ID NM_006320.4;
Protein Name Membrane-associated progesterone receptor component 2
Protein Synonyms/Alias Progesterone membrane-binding protein;Steroid receptor protein DG6;
Gene Name PGRMC2
Gene Synonyms/Alias DG6;PMBP;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Receptor for steroids.
Phosphorylation Sites
 dbPAF PTMs: 10
PositionPeptidesSourceReferences ( PMIDs )
90GAGAGEESPATSLPRdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated17081983; 18691976; 19369195; 19690332; 16381945; 23193290;
93AGEESPATSLPRMKKPhosphoSitePlus;curated22135298; 25850435; 23836654
94GEESPATSLPRMKKRPhosphoSitePlus22135298
104RMKKRDFSLEQLRQYdbPTM 3.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated20166139; 20230923; 20363803; 16381945; 23193290; 18988627;
143FYGPAGPYGIFAGRDdbPTM 3.0;PhosphoSitePlus21253578; 16381945; 23193290; 22135298
196QFKEKYDYVGRLLKPPhosphoSitePlus22135298
208LKPGEEPSEYTDEEDdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18318008; 19369195; 16381945; 23193290; 18669648; 18578522;
210PGEEPSEYTDEEDTKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 19369195; 16381945; 23193290; 18187866; 18578522;
211GEEPSEYTDEEDTKDdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18318008; 18669648; 18691976; 19413330; 16381945; 23193290;
216EYTDEEDTKDHNKQDdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated19835603; 20166139; 20230923; 20363803; 16381945; 23193290;
Sequence
(Fasta)		MAAGDGDVKL GTLGSGSESS NDGGSESPGD AGAAAEGGGW AAAALALLTG GGEMLLNVAL 60
VALVLLGAYR LWVRWGRRGL GAGAGAGEES PATSLPRMKK RDFSLEQLRQ YDGSRNPRIL 120
LAVNGKVFDV TKGSKFYGPA GPYGIFAGRD ASRGLATFCL DKDALRDEYD DLSDLNAVQM 180
ESVREWEMQF KEKYDYVGRL LKPGEEPSEY TDEEDTKDHN KQD 224
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0754--Steroid-binding
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001199--Cyt_B5-like_heme/steroid-bd
PROSITE
Pfam

PF00173--Cyt-b5
Gene Ontology

GO:0012505--C:endomembrane system
GO:0016021--C:integral component of membrane
GO:0016020--C:membrane
GO:0020037--F:heme binding
GO:0005496--F:steroid binding
GO:0003707--F:steroid hormone receptor activity
GO:0043401--P:steroid hormone mediated signaling pathway