dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000856
Uniprot Accession O15091; MRRP3_HUMAN; B4DXD9; B4E0S8; B4E211; C4AM93; D3DS99; D3DSA1; Q86SZ4; Q86YB5; Q8N5L5;
Genbank Protein ID NP_001243607.1; NP_001243608.1; NP_001243609.1; NP_001243610.1; NP_055487.2; XP_005268294.1; XP_011535711.1; XP_011535712.1; XP_011535713.1;
Genbank Nucleotide ID NM_001256678.1; NM_001256679.1; NM_001256680.1; NM_001256681.1; NM_014672.3; XM_005268237.2; XM_011537409.1; XM_011537410.1; XM_011537411.1;
Protein Name Mitochondrial ribonuclease P protein 3
Protein Synonyms/Alias
Gene Name KIAA0391
Gene Synonyms/Alias MRPP3;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
98KERSQMNSQTEDHALPhosphoSitePlus;curated22135298; 23917254
175KNNGIVSYDLLVKYLPhosphoSitePlus22135298
213KTLEPRGYSLLIRGLPhosphoSitePlus22135298
214TLEPRGYSLLIRGLIPhosphoSitePlus22135298
307KLLDILSYLRNNQLYdbPTM 3.0;PhosphoSitePlus;curated21406692; 16381945; 23193290; 22135298; 22817900
365IQLSPEEYECLKGKIPhosphoSitePlus22135298
453KHMLRRSSQWSRDEMcurated25849741
Sequence
(Fasta)		MTFYLFGIRS FPKLWKSPYL GLGPGHSYVS LFLADRCGIR NQQRLFSLKT MSPQNTKATN 60
LIAKARYLRK DEGSNKQVYS VPHFFLAGAA KERSQMNSQT EDHALAPVRN TIQLPTQPLN 120
SEEWDKLKED LKENTGKTSF ESWIISQMAG CHSSIDVAKS LLAWVAAKNN GIVSYDLLVK 180
YLYLCVFHMQ TSEVIDVFEI MKARYKTLEP RGYSLLIRGL IHSDRWREAL LLLEDIKKVI 240
TPSKKNYNDC IQGALLHQDV NTAWNLYQEL LGHDIVPMLE TLKAFFDFGK DIKDDNYSNK 300
LLDILSYLRN NQLYPGESFA HSIKTWFESV PGKQWKGQFT TVRKSGQCSG CGKTIESIQL 360
SPEEYECLKG KIMRDVIDGG DQYRKTTPQE LKRFENFIKS RPPFDVVIDG LNVAKMFPKV 420
RESQLLLNVV SQLAKRNLRL LVLGRKHMLR RSSQWSRDEM EEVQKQASCF FADDISEDDP 480
FLLYATLHSG NHCRFITRDL MRDHKACLPD AKTQRLFFKW QQGHQLAIVN RFPGSKLTFQ 540
RILSYDTVVQ TTGDSWHIPY DEDLVERCSC EVPTKWLCLH QKT 584
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0496--Mitochondrion
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0809--Transit peptide
KW-0819--tRNA processing
Interpro

IPR031595--PRORP_C
PROSITE
Pfam

PF16953--PRORP
Gene Ontology

GO:0005739--C:mitochondrion
GO:0008033--P:tRNA processing