dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000851
Uniprot Accession O15079; SNPH_HUMAN; Q8IYI3;
Genbank Protein ID NP_055538.2; XP_005260945.1;
Genbank Nucleotide ID NM_014723.2; XM_005260888.2;
Protein Name Syntaphilin
Protein Synonyms/Alias
Gene Name SNPH
Gene Synonyms/Alias KIAA0374;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Inhibits SNARE complex formation by absorbing free syntaxin-1.
Phosphorylation Sites
 dbPAF PTMs: 11
PositionPeptidesSourceReferences ( PMIDs )
11SLPGSRRTSAGSRRRPhosphoSitePlus22135298
12LPGSRRTSAGSRRRTPhosphoSitePlus22135298
19SAGSRRRTSPPVSVRPhosphoSitePlus22135298
20AGSRRRTSPPVSVRDPhosphoSitePlus22135298
29PVSVRDAYGTSSLSSPhosphoSitePlus22135298
37GTSSLSSSSNSGSYKPhosphoSitePlus22135298
43SSSNSGSYKGSDSSPPhosphoSitePlus22135298
166KDKGLQKYFVDINIQPhosphoSitePlus22135298
290LGPRFPASNTYEKLLPhosphoSitePlus22135298
455RRQGQPIYNISSLLRPhosphoSitePlus22135298
458GQPIYNISSLLRGCCPhosphoSitePlus22135298
Sequence
(Fasta)		MAMSLPGSRR TSAGSRRRTS PPVSVRDAYG TSSLSSSSNS GSYKGSDSSP TPRRSMKYTL 60
CSDNHGIKPP TPEQYLTPLQ QKEVCIRHLK ARLKDTQDRL QDRDTEIDDL KTQLSRMQED 120
WIEEECHRVE AQLALKEARK EIKQLKQVID TVKNNLIDKD KGLQKYFVDI NIQNKKLETL 180
LHSMEVAQNG MAKEDGTGES AGGSPARSLT RSSTYTKLSD PAVCGDRQPG DPSSGSAEDG 240
ADSGFAAADD TLSRTDALEA SSLLSSGVDC GTEETSLHSS FGLGPRFPAS NTYEKLLCGM 300
EAGVQASCMQ ERAIQTDFVQ YQPDLDTILE KVTQAQVCGT DPESGDRCPE LDAHPSGPRD 360
PNSAVVVTVG DELEAPEPIT RGPTPQRPGA NPNPGQSVSV VCPMEEEEEA AVAEKEPKSY 420
WSRHYIVDLL AVVVPAVPTV AWLCRSQRRQ GQPIYNISSL LRGCCTVALH SIRRISCRSL 480
SQPSPSPAGG GSQL 495
Keyword

KW-0025--Alternative splicing
KW-0965--Cell junction
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0770--Synapse
KW-0771--Synaptosome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR026196--Syntaphilin
IPR028197--Syntaphilin/Syntabulin
PROSITE
Pfam

PF15290--Syntaphilin
Gene Ontology

GO:0030054--C:cell junction
GO:0005737--C:cytoplasm
GO:0005881--C:cytoplasmic microtubule
GO:0016021--C:integral component of membrane
GO:0005739--C:mitochondrion
GO:0043005--C:neuron projection
GO:0045202--C:synapse
GO:0017075--F:syntaxin-1 binding
GO:0007269--P:neurotransmitter secretion
GO:0016081--P:synaptic vesicle docking