dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000844
Uniprot Accession O15066; KIF3B_HUMAN; B2RMP4; B4DSR5; E1P5M5;
Genbank Protein ID NP_004789.1;
Genbank Nucleotide ID NM_004798.3;
Protein Name Kinesin-like protein KIF3B
Protein Synonyms/Alias HH0048;Microtubule plus end-directed kinesin motor 3B;
Gene Name KIF3B
Gene Synonyms/Alias KIAA0359;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Involved in tethering the chromosomes to the spindle pole and in chromosome movement. Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 19
PositionPeptidesSourceReferences ( PMIDs )
49SVKNPKGTAHEMPKTPhosphoSitePlus22135298
58HEMPKTFTFDAVYDWPhosphoSitePlus22135298
122KRGVIPNSFDHIFTHPhosphoSitePlus22135298
157EEIRDLLSKDQTKRLdbPTM 3.0;PhosphoSitePlus21060948; 16381945; 23193290; 22135298
180GVYVKDLSSFVTKSVPhosphoSitePlus22135298
181VYVKDLSSFVTKSVKPhosphoSitePlus22135298
213TNMNEHSSRSHAIFVPhosphoSitePlus22135298
669LLELDMPSRTTRDYEdbPTM 3.0;HPRD 918452278; 16381945; 23193290; 18988627
671ELDMPSRTTRDYEGPdbPTM 3.0;HPRD 918452278; 16381945; 23193290; 18988627
675PSRTTRDYEGPAIAPPhosphoSitePlus22135298
723RPKSGRKSGSSSSSScurated25627689; 23917254
725KSGRKSGSSSSSSGTcurated25627689; 23186163
726SGRKSGSSSSSSGTPcurated25627689; 23090842
727GRKSGSSSSSSGTPAdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;curated18669648; 16381945; 23193290; 18988627; 25627689; 23090842;
728RKSGSSSSSSGTPASdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;curated18669648; 16381945; 23193290; 18988627; 23090842; 22817900
730SGSSSSSSGTPASQLPhosphoSitePlus22135298
732SSSSSSGTPASQLYPPhosphoSitePlus;curated22135298; 25627689; 22199227
738GTPASQLYPQSRGLVPhosphoSitePlus22135298
741ASQLYPQSRGLVPK-PhosphoSitePlus22135298
Sequence
(Fasta)		MSKLKSSESV RVVVRCRPMN GKEKAASYDK VVDVDVKLGQ VSVKNPKGTA HEMPKTFTFD 60
AVYDWNAKQF ELYDETFRPL VDSVLQGFNG TIFAYGQTGT GKTYTMEGIR GDPEKRGVIP 120
NSFDHIFTHI SRSQNQQYLV RASYLEIYQE EIRDLLSKDQ TKRLELKERP DTGVYVKDLS 180
SFVTKSVKEI EHVMNVGNQN RSVGATNMNE HSSRSHAIFV ITIECSEVGL DGENHIRVGK 240
LNLVDLAGSE RQAKTGAQGE RLKEATKINL SLSALGNVIS ALVDGKSTHI PYRDSKLTRL 300
LQDSLGGNAK TVMVANVGPA SYNVEETLTT LRYANRAKNI KNKPRVNEDP KDALLREFQE 360
EIARLKAQLE KRSIGRRKRR EKRREGGGSG GGGEEEEEEG EEGEEEGDDK DDYWREQQEK 420
LEIEKRAIVE DHSLVAEEKM RLLKEKEKKM EDLRREKDAA EMLGAKIKAM ESKLLVGGKN 480
IVDHTNEQQK ILEQKRQEIA EQKRREREIQ QQMESRDEET LELKETYSSL QQEVDIKTKK 540
LKKLFSKLQA VKAEIHDLQE EHIKERQELE QTQNELTREL KLKHLIIENF IPLEEKSKIM 600
NRAFFDEEED HWKLHPITRL ENQQMMKRPV SAVGYKRPLS QHARMSMMIR PEARYRAENI 660
VLLELDMPSR TTRDYEGPAI APKVQAALDA ALQDEDEIQV DASSFESTAN KKSKARPKSG 720
RKSGSSSSSS GTPASQLYPQ SRGLVPK 748
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
Interpro

IPR027640--Kinesin-like_fam
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
Pfam

PF00225--Kinesin
Gene Ontology

GO:0005813--C:centrosome
GO:0097542--C:ciliary tip
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0030990--C:intraciliary transport particle
GO:0016939--C:kinesin II complex
GO:0016020--C:membrane
GO:0005874--C:microtubule
GO:0015630--C:microtubule cytoskeleton
GO:0030496--C:midbody
GO:0005873--C:plus-end kinesin complex
GO:0072372--C:primary cilium
GO:0005819--C:spindle
GO:0005524--F:ATP binding
GO:0008574--F:ATP-dependent microtubule motor activity, plus-end-directed
GO:0003777--F:microtubule motor activity
GO:0017048--F:Rho GTPase binding
GO:0008089--P:anterograde axon cargo transport
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0007596--P:blood coagulation
GO:0007368--P:determination of left/right symmetry
GO:0061024--P:membrane organization
GO:0007018--P:microtubule-based movement
GO:0007100--P:mitotic centrosome separation
GO:0090307--P:mitotic spindle assembly
GO:0007052--P:mitotic spindle organization
GO:0006996--P:organelle organization
GO:0072383--P:plus-end-directed vesicle transport along microtubule
GO:0032467--P:positive regulation of cytokinesis