dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000836
Uniprot Accession O15050; TRNK1_HUMAN; Q8N8K0;
Genbank Protein ID NP_055646.2;
Genbank Nucleotide ID NM_014831.2;
Protein Name TPR and ankyrin repeat-containing protein 1
Protein Synonyms/Alias Lupus brain antigen 1 homolog;
Gene Name TRANK1
Gene Synonyms/Alias KIAA0342;LBA1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 18
PositionPeptidesSourceReferences ( PMIDs )
202SVETIGPYPLHALMRPhosphoSitePlus22135298
652PCGATARTLPEGSAVPhosphoSitePlus22135298
662EGSAVPDSWETLPGTPhosphoSitePlus22135298
669SWETLPGTQVTRKEPPhosphoSitePlus22135298
704QQVEVDPSFPEDCLQPhosphoSitePlus22135298
918IKAICNAYNRGLSCVPhosphoSitePlus22135298
1178STKATSHYKPLDPNIdbPTM 3.0;PhosphoSitePlus18083107; 16381945; 23193290; 22135298
1779LSLKCLSYAKEFQLSPhosphoSitePlus22135298
1845AAIAVEKYEEMLKTKPhosphoSitePlus22135298
1853EEMLKTKTLPISKLSPhosphoSitePlus22135298
1860TLPISKLSYSASQFYPhosphoSitePlus22135298
1861LPISKLSYSASQFYLPhosphoSitePlus22135298
1862PISKLSYSASQFYLEPhosphoSitePlus22135298
2144RSLLGKTYRGVCMRFPhosphoSitePlus22135298
2408LIPSIGNTVALLEFQPhosphoSitePlus22135298
2698SWRRRVGTQMERVREPhosphoSitePlus22135298
2741RGPENYFSPSKAFEGPhosphoSitePlus;curated22135298; 25627689; 23186163
2900GIVQEDDYENEVEDFPhosphoSitePlus22135298
Sequence
(Fasta)
MWDPRAARVP PRDLAVLLCN KSNAFFSLGK WNEAFVAAKE CLQWDPTYVK GYYRAGYSLL 60
RLHQPYEAAR MFFEGLRLVQ RSQDQAPVAD FLVGVFTTMS SDSIVLQSFL PCFDHIFTTG 120
FPTEVWQSVI EKLAKKGLWH SFLLLSAKKD RLPRNIHVPE LSLKSLFEKY VFIGLYEKME 180
QVPKLVQWLI SIGASVETIG PYPLHALMRL CIQARENHLF RWLMDHKPEW KGRINQKDGD 240
GCTVLHVVAA HSPGYLVKRQ TEDVQMLLRF GADPTLLDRQ SRSVVDVLKR NKNFKAIEKI 300
NSHLEKLATC SKDLSGFSNG DGPTSENDIF RKVLEQLVKY MNSGNRLLHK NFLKQEVVQR 360
FLRLLSTLQE IPPDLVCDIN QDCATTVFKF LLEKQRWPEV LLLLTRKVSG EPPLGDCLIK 420
DCNFSDLDIC TIIPHLSTWD QRKKQLLGCL IDSGALPDGL QESQERPVVT CLKHEDFELA 480
FLLLTKGADP RAISLTEGDT PLHAALHIFL EIKADIGFSF LSHLLDLFWS NPTEFDYLNP 540
NVQDSNGNTL MHILFQKGML KRVKKLLDLL VKFDINFNLK NKEGKDARHR IKKNDSLLLA 600
WNKALMENRR RSRQDSAAHL GKLSKSTAPG HTSQLKSQGS FKSVPCGATA RTLPEGSAVP 660
DSWETLPGTQ VTRKEPGALR PCSLRDCLMQ DITVLIQQVE VDPSFPEDCL QSSEPLEAGA 720
GKEGKKDDKP TLGAGAPDCS EVGEGHAQVG LGALQLVPDD NRGKEGNDDQ DDWSTQEIEA 780
CLQDFDNMTW EIECTSEMLK KLSSKVMTKV IKKKIILAIQ QLGNGEWTQG LQKRLKHLKG 840
SIQLFEAKLD KGARMLWELA IDFSPRCSEN PEKIIATEQN TCAMEKSGRI YTEIIRIWDI 900
VLDHCKLADS IKAICNAYNR GLSCVLRKKL KGINKGQVSA NMKIQKRIPR CYVEDTEAEK 960
GREHVNPEYF PPASAVETEY NIMKFHSFST NMAFNILNDT TATVEYPFRV GELEYAVIDL 1020
NPRPLEPIIL IGRSGTGKTT CCLYRLWKKF HVYWEKAEQA GSPLLAKQVW LKRRLEVEPG 1080
KESPGGEEEE EEEDEEEEDS IEVETVESID EQEYEACAGG AGVEPAGDGQ AAEVCAPEHP 1140
HQLEHLHQIF VTKNHVLCQE VQRNFIELSK STKATSHYKP LDPNIHKLQD LRDENFPLFV 1200
TSKQLLLLLD ASLPKPFFLR NEDGSLKRTI IGWSAQEEST IPSWQEDEEE AEVDGDYSEE 1260
DKAVEMRTGD SDPRVYVTFE VFKNEIWPKM TKGRTAYNPA LIWKEIKSFL KGSFEALSCP 1320
HGRLTEEVYK KLGRKRCPNF KEDRSEIYSL FSLYQQIRSQ KGYFDEEDVL YNISRRLSKL 1380
RVLPWSIHEL YGDEIQDFTQ AELALLMKCI NDPNSMFLTG DTAQSIMKGV AFRFSDLRSL 1440
FHYASRNTID KQCAVRKPKK IHQLYQNYRS HSGILNLASG VVDLLQFYFP ESFDRLPRDS 1500
GLFDGPKPTV LESCSVSDLA ILLRGNKRKT QPIEFGAHQV ILVANETAKE KIPEELGLAL 1560
VLTIYEAKGL EFDDVLLYNF FTDSEAYKEW KIISSFTPTS TDSREENRPL VEVPLDKPGS 1620
SQGRSLMVNP EMYKLLNGEL KQLYTAITRA RVNLWIFDEN REKRAPAFKY FIRRDFVQVV 1680
KTDENKDFDD SMFVKTSTPA EWIAQGDYYA KHQCWKVAAK CYQKGGAFEK EKLALAHDTA 1740
LSMKSKKVSP KEKQLEYLEL AKTYLECKEP TLSLKCLSYA KEFQLSAQLC ERLGKIRDAA 1800
YFYKRSQCYK DAFRCFEQIQ EFDLALKMYC QEELFEEAAI AVEKYEEMLK TKTLPISKLS 1860
YSASQFYLEA AAKYLSANKM KEMMAVLSKL DIEDQLVFLK SRKRLAEAAD LLNREGRREE 1920
AALLMKQHGC LLEAARLTAD KDFQASCLLG AARLNVARDS DIEHTKDILR EALDICYQTG 1980
QLSGIAEAHF LQGVILRDFQ KLRDAFFKFD TLNHSAGVVE ALYEAASQCE AEPEKILGLA 2040
PGGLEILLSL VRALKRVTNN AEKEMVKSCF EFFGISQVDA KYCQIAQNDP GPILRIIFDL 2100
DLNLREKKTK DHFLIMTDQV KLALNKHLLG RLCQITRSLL GKTYRGVCMR FIVGLKCEDE 2160
NCEHFHRPLR RCEAKCLVQS KMNLVAINGL LLEAKKVFPK ILAEELKEID YILSTDMYGL 2220
CKSILDVLFP KHFHQRVLSE NPMACKEILK PNYKSFRFYR FALKEYIHFL FENESARNRR 2280
ESTDLWLSAM QAFLLSSNYP EEFEKLLHQE EDNYNRELKA LESEKDERGR GRGSRIKGIE 2340
GKFGMLAPNR DDENMDKTHL CFIRLLENCI DQFYVYRNPE DYKRLFFRFM NVLIKRCKEP 2400
LIPSIGNTVA LLEFQFIHCG VVLARLWKNV ILCLPKSYIA LLHYWEFLFS KKDKELGDVF 2460
SIIQEYKPKD VTRAIQDFRF HLSYLAKVLC GYENVNFNVL LDAFSEIDYV VSGEAERTLV 2520
LCLVMLVNAE EILQPYCKPL LYRHFREIES RLQLMSMDCP GQVPERLLKV VKRVLVAVNV 2580
KSVAEALQDL LFERDEEYLM DCDWRWDPVH TKGSIVRGLY YEEVRLNRLL CLDPVDYFAE 2640
PECEFGQDEM DELALEDRDH VLATILSQKQ RKASIQRKLR RACLVVSLCI SWRRRVGTQM 2700
ERVREEAREP RAGNFKKADV DRTQCDLCGV KFTRGPENYF SPSKAFEGAA SEVAVLSRAE 2760
LEREECQERN SESYEQHIHL EHHQRQQVAY QKYSEFFHEK VDPAIDEGKL VVQDIEQSVW 2820
IHSHVGSKEH SHMLQKVQEH IKRVSDMVED LYRRKAWAGA EEAMTRLVNI LILSVRDARD 2880
WLMKTETRLK KEGIVQEDDY ENEVEDFGEL RPRRRSRKCG KQRKY 2926
Keyword

KW-0040--ANK repeat
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR027417--P-loop_NTPase
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR014016--UvrD-like_ATP-bd

PROSITE

PS50297--ANK_REP_REGION
PS50293--TPR_REGION

Pfam

PF00580--UvrD-helicase

Gene Ontology

GO:0005524--F:ATP binding