dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000834 |
| Uniprot Accession | O15047; SET1A_HUMAN; A6NP62; Q6PIF3; Q8TAJ6; |
| Genbank Protein ID | NP_055527.1; XP_005255780.1; XP_006721169.1; XP_011544296.1; XP_011544297.1; XP_011544298.1; |
| Genbank Nucleotide ID | NM_014712.2; XM_005255723.1; XM_006721106.2; XM_011545994.1; XM_011545995.1; XM_011545996.1; |
| Protein Name | Histone-lysine N-methyltransferase SETD1A |
| Protein Synonyms/Alias | Lysine N-methyltransferase 2F;SET domain-containing protein 1A;hSET1A;Set1/Ash2 histone methyltransferase complex subunit SET1; |
| Gene Name | SETD1A |
| Gene Synonyms/Alias | KIAA0339;KMT2F;SET1;SET1A; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. |
| Phosphorylation Sites |
dbPAF PTMs: 98 (View all) |