dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000833
Uniprot Accession O15042; SR140_HUMAN; A0PJ60; Q0D2M1; Q2NKQ7; Q9BR70;
Genbank Protein ID NP_001073884.1; XP_005247303.1; XP_005247306.1;
Genbank Nucleotide ID NM_001080415.1; XM_005247246.3; XM_005247249.3;
Protein Name U2 snRNP-associated SURP motif-containing protein
Protein Synonyms/Alias 140 kDa Ser/Arg-rich domain protein;U2-associated protein SR140;
Gene Name U2SURP
Gene Synonyms/Alias KIAA0332;SR140;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 76 (View all)
PositionPeptidesSourceReferences ( PMIDs )
5---MADKTPGGSQKAPhosphoSitePlus;curated22135298; 25627689
9ADKTPGGSQKASSKTPhosphoSitePlus22135298
13PGGSQKASSKTRSSDdbPTM 3.018187866; 16381945; 23193290
14GGSQKASSKTRSSDVdbPTM 3.018187866; 16381945; 23193290
23TRSSDVHSSGSSDAHPhosphoSitePlus22135298
24RSSDVHSSGSSDAHMPhosphoSitePlus;curated22135298; 23911959; 23186163; 21857030
27DVHSSGSSDAHMDAScurated23917254
34SDAHMDASGPSDSDMPhosphoSitePlus22135298
37HMDASGPSDSDMPSRPhosphoSitePlus;curated22135298; 25627689; 23911959; 23917254
43PSDSDMPSRTRPKSPPHOSIDA21081558
49PSRTRPKSPRKHNYRdbPTM 3.0;PhosphoSitePlus;curated20562096; 16381945; 23193290; 22135298; 26074081
59KHNYRNESARESLCDPhosphoSitePlus;curated22135298; 20873877
63RNESARESLCDSPHQdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated20068231; 16381945; 23193290; 17081983; 18988627; 22135298;
67ARESLCDSPHQNLSRdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated20068231; 22115753; 16381945; 23193290; 18988627; 21081558;
73DSPHQNLSRPLLENKdbPTM 3.0;HPRD 9;PHOSIDA;curated20068231; 16381945; 23193290; 18988627; 21081558
85ENKLKAFSIGKMSTAPhosphoSitePlus;curated22135298; 23186163
91FSIGKMSTAKRTLSKPhosphoSitePlus22135298
95KMSTAKRTLSKKEQEdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298
97STAKRTLSKKEQEELdbPTM 3.0;HPRD 9;PHOSIDA;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 21081558; 22135298
117EKAAAEIYEEFLAAFPhosphoSitePlus22135298
Sequence
(Fasta)		MADKTPGGSQ KASSKTRSSD VHSSGSSDAH MDASGPSDSD MPSRTRPKSP RKHNYRNESA 60
RESLCDSPHQ NLSRPLLENK LKAFSIGKMS TAKRTLSKKE QEELKKKEDE KAAAEIYEEF 120
LAAFEGSDGN KVKTFVRGGV VNAAKEEHET DEKRGKIYKP SSRFADQKNP PNQSSNERPP 180
SLLVIETKKP PLKKGEKEKK KSNLELFKEE LKQIQEERDE RHKTKGRLSR FEPPQSDSDG 240
QRRSMDAPSR RNRSSGVLDD YAPGSHDVGD PSTTNLYLGN INPQMNEEML CQEFGRFGPL 300
ASVKIMWPRT DEERARERNC GFVAFMNRRD AERALKNLNG KMIMSFEMKL GWGKAVPIPP 360
HPIYIPPSMM EHTLPPPPSG LPFNAQPRER LKNPNAPMLP PPKNKEDFEK TLSQAIVKVV 420
IPTERNLLAL IHRMIEFVVR EGPMFEAMIM NREINNPMFR FLFENQTPAH VYYRWKLYSI 480
LQGDSPTKWR TEDFRMFKNG SFWRPPPLNP YLHGMSEEQE TEAFVEEPSK KGALKEEQRD 540
KLEEILRGLT PRKNDIGDAM VFCLNNAEAA EEIVDCITES LSILKTPLPK KIARLYLVSD 600
VLYNSSAKVA NASYYRKFFE TKLCQIFSDL NATYRTIQGH LQSENFKQRV MTCFRAWEDW 660
AIYPEPFLIK LQNIFLGLVN IIEEKETEDV PDDLDGAPIE EELDGAPLED VDGIPIDATP 720
IDDLDGVPIK SLDDDLDGVP LDATEDSKKN EPIFKVAPSK WEAVDESELE AQAVTTSKWE 780
LFDQHEESEE EENQNQEEES EDEEDTQSSK SEEHHLYSNP IKEEMTESKF SKYSEMSEEK 840
RAKLREIELK VMKFQDELES GKRPKKPGQS FQEQVEHYRD KLLQREKEKE LERERERDKK 900
DKEKLESRSK DKKEKDECTP TRKERKRRHS TSPSPSRSSS GRRVKSPSPK SERSERSERS 960
HKESSRSRSS HKDSPRDVSK KAKRSPSGSR TPKRSRRSRS RSPKKSGKKS RSQSRSPHRS 1020
HKKSKKNKH
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0832--Ubl conjugation
Interpro

IPR006569--CID_dom
IPR008942--ENTH_VHS
IPR013170--mRNA_splic_Cwf21_dom
IPR012677--Nucleotide-bd_a/b_plait
IPR006903--RNA_pol_II-bd
IPR000504--RRM_dom
IPR000061--Surp
PROSITE

PS51391--CID
PS50102--RRM
PS50128--SURP
Pfam

PF04818--CTD_bind
PF08312--cwf21
PF00076--RRM_1
PF01805--Surp
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0000166--F:nucleotide binding
GO:0044822--F:poly(A) RNA binding
GO:0006396--P:RNA processing