dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000823
Uniprot Accession O15018; PDZD2_HUMAN; Q9BXD4;
Genbank Protein ID NP_835260.2; XP_005248327.1; XP_011512297.1;
Genbank Nucleotide ID NM_178140.2; XM_005248270.3; XM_011513995.1;
Protein Name PDZ domain-containing protein 2
Protein Synonyms/Alias Activated in prostate cancer protein;PDZ domain-containing protein 3;
Gene Name PDZD2
Gene Synonyms/Alias AIPC;KIAA0300;PDZK3;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 72 (View all)
PositionPeptidesSourceReferences ( PMIDs )
200NSSEPGETPTLELGDPhosphoSitePlus22135298
209TLELGDRTAKKGKRTPhosphoSitePlus22135298
304TDAPLTTSNDKRRFSPhosphoSitePlus22135298
514GGVHRLESVEEYNELPhosphoSitePlus22135298
557SSSASQEYHIVKKSTPhosphoSitePlus22135298
677RTKLVSPSLTPCSTPcurated23090842
679KLVSPSLTPCSTPTHcurated23090842
685LTPCSTPTHMSRSAScurated23090842
702FNTSGGASAGGSDEGPhosphoSitePlus22135298
710AGGSDEGSSSSLGRKPhosphoSitePlus22135298
831DEVIARSTYQESKEAPhosphoSitePlus22135298
840QESKEANSSPGLGTPPhosphoSitePlus22135298
841ESKEANSSPGLGTPLcurated23090842
846NSSPGLGTPLKSPSLPhosphoSitePlus;curated22135298; 23090842
850GLGTPLKSPSLAKKDPhosphoSitePlus;curated22135298; 23090842
920PGKPRANSLVTLGSHcurated23090842
944VTVARQASLPGSPQAPhosphoSitePlus;curated22135298; 23090842
948RQASLPGSPQALRNPPhosphoSitePlus;curated22135298; 23090842
1005EDDPRRVSISSSKGMcurated24702127
1024QEERPRKTLVSKAISPhosphoSitePlus22135298
Sequence
(Fasta)		MPITQDNAVL HLPLLYQWLQ NSLQEGGDGP EQRLCQAAIQ KLQEYIQLNF AVDESTVPPD 60
HSPPEMEICT VYLTKELGDT ETVGLSFGNI PVFGDYGEKR RGGKKRKTHQ GPVLDVGCIW 120
VTELRKNSPA GKSGKVRLRD EILSLNGQLM VGVDVSGASY LAEQCWNGGF IYLIMLRRFK 180
HKAHSTYNGN SSNSSEPGET PTLELGDRTA KKGKRTRKFG VISRPPANKA PEESKGSAGC 240
EVSSDPSTEL ENGPDPELGN GHVFQLENGP DSLKEVAGPH LERSEVDRGT EHRIPKTDAP 300
LTTSNDKRRF SKGGKTDFQS SDCLAREEVG RIWKMELLKE SDGLGIQVSG GRGSKRSPHA 360
IVVTQVKEGG AAHRDGRLSL GDELLVINGH LLVGLSHEEA VAILRSATGM VQLVVASKEN 420
SAEDLLRLTS KSLPDLTSSV EDVSSWTDNE DQEADGEEDE GTSSSVQRAM PGTDEPQDVC 480
GAEESKGNLE SPKQGSNKIK LKSRLSGGVH RLESVEEYNE LMVRNGDPRI RMLEVSRDGR 540
KHSLPQLLDS SSASQEYHIV KKSTRSLSTT QVESPWRLIR PSVISIIGLY KEKGKGLGFS 600
IAGGRDCIRG QMGIFVKTIF PNGSAAEDGR LKEGDEILDV NGIPIKGLTF QEAIHTFKQI 660
RSGLFVLTVR TKLVSPSLTP CSTPTHMSRS ASPNFNTSGG ASAGGSDEGS SSSLGRKTPG 720
PKDRIVMEVT LNKEPRVGLG IGACCLALEN SPPGIYIHSL APGSVAKMES NLSRGDQILE 780
VNSVNVRHAA LSKVHAILSK CPPGPVRLVI GRHPNPKVSE QEMDEVIARS TYQESKEANS 840
SPGLGTPLKS PSLAKKDSLI SESELSQYFA HDVPGPLSDF MVAGSEDEDH PGSGCSTSEE 900
GSLPPSTSTH KEPGKPRANS LVTLGSHRAS GLFHKQVTVA RQASLPGSPQ ALRNPLLRQR 960
KVGCYDANDA SDEEEFDREG DCISLPGALP GPIRPLSEDD PRRVSISSSK GMDVHNQEER 1020
PRKTLVSKAI SAPLLGSSVD LEESIPEGMV DAASYAANLT DSAEAPKGSP GSWWKKELSG 1080
SSSAPKLEYT VRTDTQSPTN TGSPSSPQQK SEGLGSRHRP VARVSPHCKR SEAEAKPSGS 1140
QTVNLTGRAN DPCDLDSRVQ ATSVKVTVAG FQPGGAVEKE SLGKLTTGDA CVSTSCELAS 1200
ALSHLDASHL TENLPKAASE LGQQPMTELD SSSDLISSPG KKGAAHPDPS KTSVDTGQVS 1260
RPENPSQPAS PRVTKCKARS PVRLPHEGSP SPGEKAAAPP DYSKTRSASE TSTPHNTRRV 1320
AALRGAGPGA EGMTPAGAVL PGDPLTSQEQ RQGAPGNHSK ALEMTGIHAP ESSQEPSLLE 1380
GADSVSSRAP QASLSMLPST DNTKEACGHV SGHCCPGGSR ESPVTDIDSF IKELDASAAR 1440
SPSSQTGDSG SQEGSAQGHP PAGAGGGSSC RAEPVPGGQT SSPRRAWAAG APAYPQWASQ 1500
PSVLDSINPD KHFTVNKNFL SNYSRNFSSF HEDSTSLSGL GDSTEPSLSS MYGDAEDSSS 1560
DPESLTEAPR ASARDGWSPP RSRVSLHKED PSESEEEQIE ICSTRGCPNP PSSPAHLPTQ 1620
AAICPASAKV LSLKYSTPRE SVASPREKAA CLPGSYTSGP DSSQPSSLLE MSSQEHETHA 1680
DISTSQNHRP SCAEETTEVT SASSAMENSP LSKVARHFHS PPIILSSPNM VNGLEHDLLD 1740
DETLNQYETS INAAASLSSF SVDVPKNGES VLENLHISES QDLDDLLQKP KMIARRPIMA 1800
WFKEINKHNQ GTHLRSKTEK EQPLMPARSP DSKIQMVSSS QKKGVTVPHS PPQPKTNLEN 1860
KDLSKKSPAE MLLTNGQKAK CGPKLKRLSL KGKAKVNSEA PAANAVKAGG TDHRKPLISP 1920
QTSHKTLSKA VSQRLHVADH EDPDRNTTAA PRSPQCVLES KPPLATSGPL KPSVSDTSIR 1980
TFVSPLTSPK PVPEQGMWSR FHMAVLSEPD RGCPTTPKSP KCRAEGRAPR ADSGPVSPAA 2040
SRNGMSVAGN RQSEPRLASH VAADTAQPRP TGEKGGNIMA SDRLERTNQL KIVEISAEAV 2100
SETVCGNKPA ESDRRGGCLA QGNCQEKSEI RLYRQVAESS TSHPSSLPSH ASQAEQEMSR 2160
SFSMAKLASS SSSLQTAIRK AEYSQGKSSL MSDSRGVPRN SIPGGPSGED HLYFTPRPAT 2220
RTYSMPAQFS SHFGREGHPP HSLGRSRDSQ VPVTSSVVPE AKASRGGLPS LANGQGIYSV 2280
KPLLDTSRNL PATDEGDIIS VQETSCLVTD KIKVTRRHYC YEQNWPHEST SFFSVKQRIK 2340
SFENLANADR PVAKSGASPF LSVSSKPPIG RRSSGSIVSG SLGHPGDAAA RLLRRSLSSC 2400
SENQSEAGTL LPQMAKSPSI MTLTISRQNP PETSSKGSDS ELKKSLGPLG IPTPTMTLAS 2460
PVKRNKSSVR HTQPSPVSRS KLQELRALSM PDLDKLCSED YSAGPSAVLF KTELEITPRR 2520
SPGPPAGGVS CPEKGGNRAC PGGSGPKTSA AETPSSASDT GEAAQDLPFR RSWSVNLDQL 2580
LVSAGDQQRL QSVLSSVGSK STILTLIQEA KAQSENEEDV CFIVLNRKEG SGLGFSVAGG 2640
TDVEPKSITV HRVFSQGAAS QEGTMNRGDF LLSVNGASLA GLAHGNVLKV LHQAQLHKDA 2700
LVVIKKGMDQ PRPSARQEPP TANGKGLLSR KTIPLEPGIG RSVAVHDALC VEVLKTSAGL 2760
GLSLDGGKSS VTGDGPLVIK RVYKGGAAEQ AGIIEAGDEI LAINGKPLVG LMHFDAWNIM 2820
KSVPEGPVQL LIRKHRNSS
Keyword

KW-0025--Alternative splicing
KW-0130--Cell adhesion
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0256--Endoplasmic reticulum
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0964--Secreted
Interpro

IPR001478--PDZ
PROSITE

PS50106--PDZ
Pfam

PF00595--PDZ
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0005783--C:endoplasmic reticulum
GO:0005576--C:extracellular region
GO:0005634--C:nucleus
GO:0007155--P:cell adhesion