dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000822 |
| Uniprot Accession | O15016; TRI66_HUMAN; Q9BQQ4; |
| Genbank Protein ID | NP_055633.1; |
| Genbank Nucleotide ID | NM_014818.1; |
| Protein Name | Tripartite motif-containing protein 66 |
| Protein Synonyms/Alias | |
| Gene Name | TRIM66 |
| Gene Synonyms/Alias | C11orf29;KIAA0298; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
May function as transcription repressor; The repressive effects are mediated, at least in part, by recruitment of deacetylase activity. May play a role as negative regulator of postmeiotic genes acting through CBX3 complex formation and centromere association (By similarity). |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MARNCSECKE KRAAHILCTY CNRWLCSSCT EEHRHSPVPG GPFFPRAQKG SPGVNGGPGD 60 FTLYCPLHTQ EVLKLFCETC DMLTCHSCLV VEHKEHRCRH VEEVLQNQRM LLEGVTTQVA 120 HKKSSLQTSA KQIEDRIFEV KHQHRKVENQ IKMAKMVLMN ELNKQANGLI EELEGITNER 180 KRKLEQQLQS IMVLNRQFEH VQNFINWAVC SKTSVPFLFS KELIVFQMQR LLETSCNTDP 240 GSPWSIRFTW EPNFWTKQLA SLGCITTEGG QMSRADAPAY GGLQGSSPFY QSHQSPVAQQ 300 EALSHPSHKF QSPAVCSSSV CCSHCSPVSP SLKGQVPPPS IHPAHSFRQP PEMVPQQLGS 360 LQCSALLPRE KELACSPHPP KLLQPWLETQ PPVEQESTSQ RLGQQLTSQP VCIVPPQDVQ 420 QGAHAQPTLQ TPSIQVQFGH HQKLKLSHFQ QQPQQQLPPP PPPLPHPPPP LPPPPQQPHP 480 PLPPSQHLAS SQHESPPGPA CSQNMDIMHH KFELEEMQKD LELLLQAQQP SLQLSQTKSP 540 QHLQQTIVGQ INYIVRQPAP VQSQSQEETL QATDEPPASQ GSKPALPLDK NTAAALPQAS 600 GEETPLSVPP VDSTIQHSSP NVVRKHSTSL SIMGFSNTLE MELSSTRLER PLEPQIQSVS 660 NLTAGAPQAV PSLLSAPPKM VSSLTSVQNQ AMPSLTTSHL QTVPSLVHST FQSMPNLISD 720 SPQAMASLAS DHPQAGPSLM SGHTQAVPSL ATCPLQSIPP VSDMQPETGS SSSSGRTSGS 780 LCPRDGADPS LENALCKVKL EEPINLSVKK PPLAPVVSTS TALQQYQNPK ECENFEQGAL 840 ELDAKENQSI RAFNSEHKIP YVRLERLKIC AASSGEMPVF KLKPQKNDQD GSFLLIIECG 900 TESSSMSIKV SQDRLSEATQ APGLEGRKVT VTSLAGQRPP EVEGTSPEEH RLIPRTPGAK 960 KGPPAPIENE DFCAVCLNGG ELLCCDRCPK VFHLSCHVPA LLSFPGGEWV CTLCRSLTQP 1020 EMEYDCENAC YNQPGMRASP GLSMYDQKKC EKLVLSLCCN NLSLPFHEPV SPLARHYYQI 1080 IKRPMDLSII RRKLQKKDPA HYTTPEEVVS DVRLMFWNCA KFNYPDSEVA EAGRCLEVFF 1140 EGWLKEIYPE KRFAQPRQED SDSEEVSSES GCSTPQGFPW PPYMQEGIQP KRRRRHMENE 1200 RAKRMSFRLA NSISQV 1217 |
| Keyword | KW-0025--Alternative splicing |
| Interpro | IPR003649--Bbox_C |
| PROSITE | PS50014--BROMODOMAIN_2 |
| Pfam | |
| Gene Ontology | GO:0016235--C:aggresome |