dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000821
Uniprot Accession O15015; ZN646_HUMAN; Q8IVD8;
Genbank Protein ID NP_055514.3; XP_005255767.1; XP_005255768.1; XP_011544292.1;
Genbank Nucleotide ID NM_014699.3; XM_005255710.2; XM_005255711.2; XM_011545990.1;
Protein Name Zinc finger protein 646
Protein Synonyms/Alias
Gene Name ZNF646
Gene Synonyms/Alias KIAA0296;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May be involved in transcriptional regulation.
Phosphorylation Sites
 dbPAF PTMs: 29 (View all)
PositionPeptidesSourceReferences ( PMIDs )
33HRELLHPSPNQDSEEPhosphoSitePlus22135298
38HPSPNQDSEEADSIPPhosphoSitePlus22135298
121TPHLQGETVSTDSWGPhosphoSitePlus22135298
398NHRKSHQTGVYPCSLPhosphoSitePlus22135298
486SLVNHRHSHRTGEYQPHOSIDA;SysPTM 2.021081558; 17081983; 19366988
495RTGEYQCSLCPRKYPPhosphoSitePlus22135298
521HCKAARRSADIGAEGPhosphoSitePlus;curated22135298; 25627689
566EEEATDITPAADKTAPhosphoSitePlus;curated22135298; 25627689
607GEKENSRTETTMSPPcurated23403867
610ENSRTETTMSPPRAFcurated23403867
612SRTETTMSPPRAFACPhosphoSitePlus;curated22135298; 25850435; 23911959
930AEAAPARSPPLQLSEdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated18452278; 16381945; 23193290; 18988627; 22135298; 25850435;
936RSPPLQLSEAELLNQcurated23663014; 24667141
972QTYDDLGSLERHHQScurated23186163
991TTADKAPSPLGVAGDPhosphoSitePlus;curated22135298; 25627689
1006AMEMVVDSVLEDIVNdbPTM 3.0;HPRD 9;SysPTM 2.0;curated17081983; 16381945; 23193290; 18988627; 19366988; 24260401
1261DPRRFRCSECGKAFRPhosphoSitePlus22135298
1378RSFPGRGSLERHLREPHOSIDA;SysPTM 2.021081558; 17081983; 19366988
1440VPRPGERSQSPIRAAcurated23090842
1442RPGERSQSPIRAASSPhosphoSitePlus;curated22135298; 25627689; 22199227
Sequence
(Fasta)		MEDTPPSLSC SDCQRHFPSL PELSRHRELL HPSPNQDSEE ADSIPRPYRC QQCGRGYRHP 60
GSLVNHRRTH ETGLFPCTTC GKDFSNPMAL KSHMRTHAPE GRRRHRPPRP KEATPHLQGE 120
TVSTDSWGQR LGSSEGWENQ TKHTEETPDC ESVPDPRAAS GTWEDLPTRQ REGLASHPGP 180
EDGADGWGPS TNSARAPPLP IPASSLLSNL EQYLAESVVN FTGGQEPTQS PPAEEERRYK 240
CSQCGKTYKH AGSLTNHRQS HTLGIYPCAI CFKEFSNLMA LKNHSRLHAQ YRPYHCPHCP 300
RVFRLPRELL EHQQSHEGER QEPRWEEKGM PTTNGHTDES SQDQLPSAQM LNGSAELSTS 360
GELEDSGLEE YRPFRCGDCG RTYRHAGSLI NHRKSHQTGV YPCSLCSKQL FNAAALKNHV 420
RAHHRPRQGV GENGQPSVPP APLLLAETTH KEEEDPTTTL DHRPYKCSEC GRAYRHRGSL 480
VNHRHSHRTG EYQCSLCPRK YPNLMALRNH VRVHCKAARR SADIGAEGAP SHLKVELPPD 540
PVEAEAAPHT DQDHVCKHEE EATDITPAAD KTAAHICSIC GLLFEDAESL ERHGLTHGAG 600
EKENSRTETT MSPPRAFACR DCGKSYRHSG SLINHRQTHQ TGDFSCGACA KHFHTMAAMK 660
NHLRRHSRRR SRRHRKRAGG ASGGREAKLL AAESWTRELE DNEGLESPQD PSGESPHGAE 720
GNLESDGDCL QAESEGDKCG LERDETHFQG DKESGGTGEG LERKDASLLD NLDIPGEEGG 780
GTHFCDSLTG VDEDQKPATG QPNSSSHSAN AVTGWQAGAA HTCSDCGHSF PHATGLLSHR 840
PCHPPGIYQC SLCPKEFDSL PALRSHFQNH RPGEATSAQP FLCCLCGMIF PGRAGYRLHR 900
RQAHSSSGMT EGSEEEGEEE GVAEAAPARS PPLQLSEAEL LNQLQREVEA LDSAGYGHIC 960
GCCGQTYDDL GSLERHHQSQ SSGTTADKAP SPLGVAGDAM EMVVDSVLED IVNSVSGEGG 1020
DAKSQEGAGT PLGDSLCIQG GESLLEAQPR PFRCNQCGKT YRHGGSLVNH RKIHQTGDFL 1080
CPVCSRCYPN LAAYRNHLRN HPRCKGSEPQ VGPIPEAAGS SELQVGPIPE GGSNKPQHMA 1140
EEGPGQAEVE KLQEELKVEP LEEVARVKEE VWEETTVKGE EIEPRLETAE KGCQTEASSE 1200
RPFSCEVCGR SYKHAGSLIN HRQSHQTGHF GCQACSKGFS NLMSLKNHRR IHADPRRFRC 1260
SECGKAFRLR KQLASHQRVH MERRGGGGTR KATREDRPFR CGQCGRTYRH AGSLLNHRRS 1320
HETGQYSCPT CPKTYSNRMA LKDHQRLHSE NRRRRAGRSR RTAVRCALCG RSFPGRGSLE 1380
RHLREHEETE REPANGQGGL DGTAASEANL TGSQGLETQL GGAEPVPHLE DGVPRPGERS 1440
QSPIRAASSE APEPLSWGAG KAGGWPVGGG LGNHSGGWVP QFLTRSEEPE DSVHRSPCHA 1500
GDCQLNGPTL SHMDSWDNRD NSSQLQPGSH SSCSQCGKTY CQSGSLLNHN TNKTDRHYCL 1560
LCSKEFLNPV ATKSHSHNHI DAQTFACPDC GKAFESHQEL ASHLQAHARG HSQVPAQMEE 1620
ARDPKAGTGE DQVVLPGQGK AQEAPSETPR GPGESVERAR GGQAVTSMAA EDKERPFRCT 1680
QCGRSYRHAG SLLNHQKAHT TGLYPCSLCP KLLPNLLSLK NHSRTHTDPK RHCCSICGKA 1740
FRTAARLEGH GRVHAPREGP FTCPHCPRHF RRRISFVQHQ QQHQEEWTVA GSGRGHEGSQ 1800
EEVGTQWRGK SSPKVGGGAR SERREPRGF
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd
PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00096--zf-C2H2
PF13912--zf-C2H2_6
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated