dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000817
Uniprot Accession O14990; IPP4_HUMAN; Q5H958;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Putative type-1 protein phosphatase inhibitor 4
Protein Synonyms/Alias
Gene Name PPP1R2P9
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Functions as a protein phosphatase inhibitor. It inhibits activity of the catalytic subunit of PP1 and weakly inhibits the activity of myosin-associated phosphates.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
19KGILKNKSSSGSSVAPhosphoSitePlus22135298
20GILKNKSSSGSSVATPhosphoSitePlus22135298
28SGSSVATSGQQSGGTPhosphoSitePlus22135298
Sequence
(Fasta)
MSASTSSHRP IKGILKNKSS SGSSVATSGQ QSGGTIQDVK RKKSQKWDES SILAAHRATY 60
RDYDLMKANE PGTSYMSVQD NGEDSVRDVE GEDSVRGVEG KEATDASDHS CEVDEQESSE 120
AYMRKILLHK QEKKRQFEMR RRLHYNEELN IKLARQLMWK ELQSEDNENE ETPQGTNEEK 180
TAAEESEEAP LTGGLQTQSC DP 203
Keyword

KW-0181--Complete proteome
KW-0650--Protein phosphatase inhibitor
KW-1185--Reference proteome

Interpro

IPR007062--PPI-2

PROSITE
Pfam

PF04979--IPP-2

Gene Ontology

GO:0000164--C:protein phosphatase type 1 complex
GO:0004864--F:protein phosphatase inhibitor activity
GO:0043086--P:negative regulation of catalytic activity
GO:0043666--P:regulation of phosphoprotein phosphatase activity
GO:0009966--P:regulation of signal transduction