Tag |
Content |
dbPAF ID |
dbPAF-0000800 |
Uniprot Accession |
O14949; QCR8_HUMAN; Q5FVE2; Q9BV88; Q9T2V7; |
Genbank Protein ID |
NP_055217.2; |
Genbank Nucleotide ID |
NM_014402.4; |
Protein Name |
Cytochrome b-c1 complex subunit 8 |
Protein Synonyms/Alias |
Complex III subunit 8;Complex III subunit VIII;Ubiquinol-cytochrome c reductase complex 9.5 kDa protein;Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C; |
Gene Name |
UQCRQ |
Gene Synonyms/Alias |
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Organism |
Homo sapiens(Human) |
NCBI Taxa ID |
9606 |
Functional Description (View all) |
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.Functional Description
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
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Phosphorylation Sites
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dbPAF PTMs: 3 Position | Peptides | Source | References ( PMIDs ) |
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16 | TRMRHVISYSLSPFE | PhosphoSitePlus;curated | 22135298; 23917254 | 17 | RMRHVISYSLSPFEQ | PhosphoSitePlus | 22135298 | 32 | RAYPHVFTKGIPNVL | PhosphoSitePlus | 22135298 |
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Sequence (Fasta) | MGREFGNLTR MRHVISYSLS PFEQRAYPHV FTKGIPNVLR RIRESFFRVV PQFVVFYLIY 60 TWGTEEFERS KRKNPAAYEN DK
83Fasta Sequence
>O14949|UQCRQ|Homo sapiens(Human) MGREFGNLTRMRHVISYSLSPFEQRAYPHVFTKGIPNVLRRIRESFFRVVPQFVVFYLIYTWGTEEFERSKRKNPAAYENDK
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Keyword |
KW-0007--Acetylation KW-0181--Complete proteome KW-0903--Direct protein sequencing KW-0225--Disease mutation KW-0249--Electron transport KW-1017--Isopeptide bond KW-0472--Membrane KW-0496--Mitochondrion KW-0999--Mitochondrion inner membrane KW-1185--Reference proteome KW-0679--Respiratory chain KW-0813--Transport KW-0832--Ubl conjugation
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Interpro |
IPR004205--Cyt_bc1_su8
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PROSITE |
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Pfam |
PF02939--UcrQ
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Gene Ontology |
GO:0005743--C:mitochondrial inner membrane GO:0005739--C:mitochondrion GO:0070469--C:respiratory chain GO:0008121--F:ubiquinol-cytochrome-c reductase activity GO:0044237--P:cellular metabolic process GO:0021680--P:cerebellar Purkinje cell layer development GO:0021766--P:hippocampus development GO:0021854--P:hypothalamus development GO:0030901--P:midbrain development GO:0021548--P:pons development GO:0021860--P:pyramidal neuron development GO:0022904--P:respiratory electron transport chain GO:0044281--P:small molecule metabolic process GO:0021539--P:subthalamus development GO:0021794--P:thalamus development
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