dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000800
Uniprot Accession O14949; QCR8_HUMAN; Q5FVE2; Q9BV88; Q9T2V7;
Genbank Protein ID NP_055217.2;
Genbank Nucleotide ID NM_014402.4;
Protein Name Cytochrome b-c1 complex subunit 8
Protein Synonyms/Alias Complex III subunit 8;Complex III subunit VIII;Ubiquinol-cytochrome c reductase complex 9.5 kDa protein;Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C;
Gene Name UQCRQ
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This subunit, together with cytochrome b, binds to ubiquinone.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
16TRMRHVISYSLSPFEPhosphoSitePlus;curated22135298; 23917254
17RMRHVISYSLSPFEQPhosphoSitePlus22135298
32RAYPHVFTKGIPNVLPhosphoSitePlus22135298
Sequence
(Fasta)
MGREFGNLTR MRHVISYSLS PFEQRAYPHV FTKGIPNVLR RIRESFFRVV PQFVVFYLIY 60
TWGTEEFERS KRKNPAAYEN DK 83
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0225--Disease mutation
KW-0249--Electron transport
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0813--Transport
KW-0832--Ubl conjugation

Interpro

IPR004205--Cyt_bc1_su8

PROSITE
Pfam

PF02939--UcrQ

Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005739--C:mitochondrion
GO:0070469--C:respiratory chain
GO:0008121--F:ubiquinol-cytochrome-c reductase activity
GO:0044237--P:cellular metabolic process
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0021766--P:hippocampus development
GO:0021854--P:hypothalamus development
GO:0030901--P:midbrain development
GO:0021548--P:pons development
GO:0021860--P:pyramidal neuron development
GO:0022904--P:respiratory electron transport chain
GO:0044281--P:small molecule metabolic process
GO:0021539--P:subthalamus development
GO:0021794--P:thalamus development