dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000792
Uniprot Accession O14925; TIM23_HUMAN; Q53FF8; Q5T1E6; Q6P5S5;
Genbank Protein ID NP_006318.1;
Genbank Nucleotide ID NM_006327.3;
Protein Name Mitochondrial import inner membrane translocase subunit Tim23
Protein Synonyms/Alias
Gene Name TIMM23
Gene Synonyms/Alias TIM23;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
157GAEDDLNTVAAGTMTcurated22817900
162LNTVAAGTMTGMLYKcurated22817900
164TVAAGTMTGMLYKCTPhosphoSitePlus22135298
168GTMTGMLYKCTGGLRPhosphoSitePlus;curated22135298; 22817900
208KGSLLQQSL------curated25262027
Sequence
(Fasta)		MEGGGGSGNK TTGGLAGFFG AGGAGYSHAD LAGVPLTGMN PLSPYLNVDP RYLVQDTDEF 60
ILPTGANKTR GRFELAFFTI GGCCMTGAAF GAMNGLRLGL KETQNMAWSK PRNVQILNMV 120
TRQGALWANT LGSLALLYSA FGVIIEKTRG AEDDLNTVAA GTMTGMLYKC TGGLRGIARG 180
GLTGLTLTSL YALYNNWEHM KGSLLQQSL
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0496--Mitochondrion
KW-0999--Mitochondrion inner membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0811--Translocation
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR003397--Tim17/Tim22/Tim23/PMP24
IPR005681--Tim23
PROSITE
Pfam

PF02466--Tim17
Gene Ontology

GO:0031305--C:integral component of mitochondrial inner membrane
GO:0005743--C:mitochondrial inner membrane
GO:0005744--C:mitochondrial inner membrane presequence translocase complex
GO:0005758--C:mitochondrial intermembrane space
GO:0005739--C:mitochondrion
GO:0015450--F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GO:0015266--F:protein channel activity
GO:0044267--P:cellular protein metabolic process
GO:0030150--P:protein import into mitochondrial matrix
GO:0006626--P:protein targeting to mitochondrion