dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000786
Uniprot Accession O14908; GIPC1_HUMAN; A8K4I3; A8MZG3; Q9BTC9;
Genbank Protein ID NP_005707.1; NP_974197.1; NP_974198.1; NP_974199.1; NP_974223.1; XP_011525945.1;
Genbank Nucleotide ID NM_005716.3; NM_202468.2; NM_202469.2; NM_202470.2; NM_202494.2; XM_011527643.1;
Protein Name PDZ domain-containing protein GIPC1
Protein Synonyms/Alias GAIP C-terminus-interacting protein;RGS-GAIP-interacting protein;RGS19-interacting protein 1;Synectin;Tax interaction protein 2;TIP-2;
Gene Name GIPC1
Gene Synonyms/Alias C19orf3;GIPC;RGS19IP1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May be involved in G protein-linked signaling.
Phosphorylation Sites
 dbPAF PTMs: 13
PositionPeptidesSourceReferences ( PMIDs )
68HTQLAHGSPTGRIEGPhosphoSitePlus;curated22135298; 23186163; 20873877
70QLAHGSPTGRIEGFTcurated23186163
154ITDNGAGYAFIKRIKPhosphoSitePlus;curated22135298; 22817900
173IDHIHLISVGDMIEAPhosphoSitePlus22135298
185IEAINGQSLLGCRHYPhosphoSitePlus22135298
222RKAFDMISQRSAGGRPhosphoSitePlus;curated22135298; 23917254; 23186163
225FDMISQRSAGGRPGSdbPTM 3.0;PhosphoSitePlus;UniProt;curated20363803; 21406692; 16381945; 23193290; 22135298; 23917254;
232SAGGRPGSGPQLGTGdbPTM 3.0;PhosphoSitePlus;UniProt;curated20363803; 21406692; 16381945; 23193290; 22135298; 24275569;
238GSGPQLGTGRGTLRLPhosphoSitePlus;curated22135298; 25850435; 23898821
242QLGTGRGTLRLRSRGPhosphoSitePlus;curated22135298; 23898821; 24961811
247RGTLRLRSRGPATVEPhosphoSitePlus;curated22135298; 25627689; 23186163; 24961811
252LRSRGPATVEDLPSAPhosphoSitePlus22135298
275VDDLLESYMGIRDTEdbPTM 3.0;PhosphoSitePlus;curated18083107; 16381945; 23193290; 22135298; 22817900
Sequence
(Fasta)		MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF 60
HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE 120
DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA 180
INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR 240
GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL 300
AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY 334
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR001478--PDZ
IPR017379--UCP038083_PDZ
PROSITE

PS50106--PDZ
Pfam

PF00595--PDZ
Gene Ontology

GO:0005903--C:brush border
GO:0005938--C:cell cortex
GO:0005737--C:cytoplasm
GO:0016023--C:cytoplasmic membrane-bounded vesicle
GO:0005829--C:cytosol
GO:0043198--C:dendritic shaft
GO:0043197--C:dendritic spine
GO:0030139--C:endocytic vesicle
GO:0070062--C:extracellular exosome
GO:0016020--C:membrane
GO:0008021--C:synaptic vesicle
GO:0012506--C:vesicle membrane
GO:0003779--F:actin binding
GO:0017022--F:myosin binding
GO:0042803--F:protein homodimerization activity
GO:0005102--F:receptor binding
GO:0043542--P:endothelial cell migration
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0014047--P:glutamate secretion
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032467--P:positive regulation of cytokinesis
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:0006605--P:protein targeting
GO:0031647--P:regulation of protein stability
GO:0048167--P:regulation of synaptic plasticity
GO:0007268--P:synaptic transmission