dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000784
Uniprot Accession O14905; WNT9B_HUMAN; Q6UXT4; Q96Q09;
Genbank Protein ID NP_003387.1;
Genbank Nucleotide ID NM_003396.1;
Protein Name Protein Wnt-9b
Protein Synonyms/Alias Protein Wnt-14b;Protein Wnt-15;
Gene Name WNT9B
Gene Synonyms/Alias WNT14B;WNT15;UNQ6973/PRO21956;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
174KYSTKFLSNFLGSKRPhosphoSitePlus22135298
306GTAGRVCSREASCSSPhosphoSitePlus22135298
Sequence
(Fasta)
MRPPPALALA GLCLLALPAA AASYFGLTGR EVLTPFPGLG TAAAPAQGGA HLKQCDLLKL 60
SRRQKQLCRR EPGLAETLRD AAHLGLLECQ FQFRHERWNC SLEGRMGLLK RGFKETAFLY 120
AVSSAALTHT LARACSAGRM ERCTCDDSPG LESRQAWQWG VCGDNLKYST KFLSNFLGSK 180
RGNKDLRARA DAHNTHVGIK AVKSGLRTTC KCHGVSGSCA VRTCWKQLSP FRETGQVLKL 240
RYDSAVKVSS ATNEALGRLE LWAPARQGSL TKGLAPRSGD LVYMEDSPSF CRPSKYSPGT 300
AGRVCSREAS CSSLCCGRGY DTQSRLVAFS CHCQVQWCCY VECQQCVQEE LVYTCKH 358
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-1015--Disulfide bond
KW-0272--Extracellular matrix
KW-0325--Glycoprotein
KW-0449--Lipoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0879--Wnt signaling pathway

Interpro

IPR005817--Wnt
IPR026535--WNT9B
IPR018161--Wnt_CS

PROSITE

PS00246--WNT1

Pfam

PF00110--wnt

Gene Ontology

GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0005578--C:proteinaceous extracellular matrix
GO:0005109--F:frizzled binding
GO:0001658--P:branching involved in ureteric bud morphogenesis
GO:0060070--P:canonical Wnt signaling pathway
GO:0045165--P:cell fate commitment
GO:0007267--P:cell-cell signaling
GO:0071300--P:cellular response to retinoic acid
GO:0009267--P:cellular response to starvation
GO:0072044--P:collecting duct development
GO:0061303--P:cornea development in camera-type eye
GO:0048701--P:embryonic cranial skeleton morphogenesis
GO:0072046--P:establishment of planar polarity involved in nephron morphogenesis
GO:0001701--P:in utero embryonic development
GO:0072003--P:kidney rudiment formation
GO:0030539--P:male genitalia development
GO:0072038--P:mesenchymal stem cell maintenance involved in nephron morphogenesis
GO:0072181--P:mesonephric duct formation
GO:0072174--P:metanephric tubule formation
GO:0007275--P:multicellular organismal development
GO:0030182--P:neuron differentiation
GO:0060021--P:palate development
GO:0043085--P:positive regulation of catalytic activity
GO:0009786--P:regulation of asymmetric cell division
GO:0003339--P:regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0001932--P:regulation of protein phosphorylation
GO:0035150--P:regulation of tube size
GO:0032526--P:response to retinoic acid
GO:0061038--P:uterus morphogenesis
GO:0016055--P:Wnt signaling pathway
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway