dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000776
Uniprot Accession O14863; ZNT4_HUMAN; Q8TC39;
Genbank Protein ID NP_037441.2; XP_011520299.1;
Genbank Nucleotide ID NM_013309.4; XM_011521997.1;
Protein Name Zinc transporter 4
Protein Synonyms/Alias
Gene Name SLC30A4
Gene Synonyms/Alias ZNT4;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
12GAWKRLKSMLRKDDAPhosphoSitePlus22135298
309KIADPICTYVFSLLVcurated25404012
313PICTYVFSLLVAFTTPhosphoSitePlus22135298
319FSLLVAFTTFRIIWDcurated25404012
412RCTIQLQSYRQEVDRPhosphoSitePlus22135298
Sequence
(Fasta)
MAGSGAWKRL KSMLRKDDAP LFLNDTSAFD FSDEAGDEGL SRFNKLRVVV ADDGSEAPER 60
PVNGAHPTLQ ADDDSLLDQD LPLTNSQLSL KVDSCDNCSK QREILKQRKV KARLTIAAVL 120
YLLFMIGELV GGYIANSLAI MTDALHMLTD LSAIILTLLA LWLSSKSPTK RFTFGFHRLE 180
VLSAMISVLL VYILMGFLLY EAVQRTIHMN YEINGDIMLI TAAVGVAVNV IMGFLLNQSG 240
HRHSHSHSLP SNSPTRGSGC ERNHGQDSLA VRAAFVHALG DLVQSVGVLI AAYIIRFKPE 300
YKIADPICTY VFSLLVAFTT FRIIWDTVVI ILEGVPSHLN VDYIKEALMK IEDVYSVEDL 360
NIWSLTSGKS TAIVHIQLIP GSSSKWEEVQ SKANHLLLNT FGMYRCTIQL QSYRQEVDRT 420
CANCQSSSP
Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0406--Ion transport
KW-0458--Lysosome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
KW-0862--Zinc
KW-0864--Zinc transport

Interpro

IPR002524--Cation_efflux
IPR027469--Cation_efflux_TMD

PROSITE
Pfam

PF01545--Cation_efflux

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016023--C:cytoplasmic membrane-bounded vesicle
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0031902--C:late endosome membrane
GO:0005765--C:lysosomal membrane
GO:0016020--C:membrane
GO:0005385--F:zinc ion transmembrane transporter activity
GO:0061088--P:regulation of sequestering of zinc ion
GO:0009636--P:response to toxic substance
GO:0010043--P:response to zinc ion
GO:0071577--P:zinc II ion transmembrane transport
GO:0055069--P:zinc ion homeostasis