| Tag |
Content |
| dbPAF ID |
dbPAF-0000769 |
| Uniprot Accession |
O14829; PPE1_HUMAN; A6NHP4; A8K348; O15253; Q9NU21; Q9UJH0;
|
| Genbank Protein ID |
NP_006231.2; NP_689410.1; NP_689412.1; XP_005274610.1;
|
| Genbank Nucleotide ID |
NM_006240.2; NM_152224.1; NM_152226.1; XM_005274553.2;
|
| Protein Name |
Serine/threonine-protein phosphatase with EF-hands 1 |
| Protein Synonyms/Alias |
|
| Gene Name |
PPEF1 |
| Gene Synonyms/Alias |
PPEF;PPP7C; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
May have a role in the recovery or adaptation response of photoreceptors. May have a role in development.Functional Description
May have a role in the recovery or adaptation response of photoreceptors. May have a role in development. |
Phosphorylation Sites
|
dbPAF PTMs: 7 |
Sequence
(Fasta) | MGCSSSSTKT RRSDTSLRAA LIIQNWYRGY KARLKARQHY ALTIFQSIEY ADEQGQMQLS 60
TFFSFMLENY THIHKEELEL RNQSLESEQD MRDRWDYVDS IDVPDSYNGP RLQFPLTCTD 120
IDLLLEAFKE QQILHAHYVL EVLFETKKVL KQMPNFTHIQ TSPSKEVTIC GDLHGKLDDL 180
FLIFYKNGLP SERNPYVFNG DFVDRGKNSI EILMILCVSF LVYPNDLHLN RGNHEDFMMN 240
LRYGFTKEIL HKYKLHGKRI LQILEEFYAW LPIGTIVDNE ILVIHGGISE TTDLNLLHRV 300
ERNKMKSVLI PPTETNRDHD TDSKHNKVGV TFNAHGRIKT NGSPTEHLTE HEWEQIIDIL 360
WSDPRGKNGC FPNTCRGGGC YFGPDVTSKI LNKYQLKMLI RSHECKPEGY EICHDGKVVT 420
IFSASNYYEE GSNRGAYIKL CSGTTPRFFQ YQVTKATCFQ PLRQRVDTME NSAIKILRER 480
VISRKSDLTR AFQLQDHRKS GKLSVSQWAF CMENILGLNL PWRSLSSNLV NIDQNGNVEY 540
MSSFQNIRIE KPVQEAHSTL VETLYRYRSD LEIIFNAIDT DHSGLISVEE FRAMWKLFSS 600
HYNVHIDDSQ VNKLANIMDL NKDGSIDFNE FLKAFYVVHR YEDLMKPDVT NLG
654Fasta Sequence
>O14829|PPEF1|Homo sapiens(Human)
MGCSSSSTKTRRSDTSLRAALIIQNWYRGYKARLKARQHYALTIFQSIEYADEQGQMQLSTFFSFMLENYTHIHKEELELRNQSLESEQDMRDRWDYVDSIDVPDSYNGPRLQFPLTCTDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTKATCFQPLRQRVDTMENSAIKILRERVISRKSDLTRAFQLQDHRKSGKLSVSQWAFCMENILGLNLPWRSLSSNLVNIDQNGNVEYMSSFQNIRIEKPVQEAHSTLVETLYRYRSDLEIIFNAIDTDHSGLISVEEFRAMWKLFSSHYNVHIDDSQVNKLANIMDLNKDGSIDFNEFLKAFYVVHRYEDLMKPDVTNLG
|
| Keyword |
KW-0025--Alternative splicing
KW-0106--Calcium
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0621--Polymorphism
KW-0904--Protein phosphatase
KW-1185--Reference proteome
KW-0677--Repeat
|
| Interpro |
IPR004843--Calcineurin-like_PHP_apaH
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000048--IQ_motif_EF-hand-BS
IPR029052--Metallo-depent_PP-like
IPR013235--PPP_dom
IPR012008--Ser/Thr-Pase_EF-hand_contain
IPR006186--Ser/Thr-sp_prot-phosphatase
|
| PROSITE |
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50096--IQ
PS00125--SER_THR_PHOSPHATASE
|
| Pfam |
PF13499--EF-hand_7
PF00612--IQ
PF00149--Metallophos
PF08321--PPP5
|
| Gene Ontology |
GO:0005829--C:cytosol
GO:0005509--F:calcium ion binding
GO:0005506--F:iron ion binding
GO:0030145--F:manganese ion binding
GO:0004722--F:protein serine/threonine phosphatase activity
GO:0050906--P:detection of stimulus involved in sensory perception
GO:0007603--P:phototransduction, visible light
GO:0006470--P:protein dephosphorylation
GO:0022400--P:regulation of rhodopsin mediated signaling pathway
GO:0016056--P:rhodopsin mediated signaling pathway
|
