dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000762
Uniprot Accession O14807; RASM_HUMAN; B4DIK0; Q86WX8;
Genbank Protein ID NP_001078518.1; NP_001239019.1; NP_001239020.1; NP_001239021.1; NP_001239022.1; NP_036351.3; XP_005247285.1;
Genbank Nucleotide ID NM_001085049.2; NM_001252090.1; NM_001252091.1; NM_001252092.1; NM_001252093.1; NM_012219.4; XM_005247228.1;
Protein Name Ras-related protein M-Ras
Protein Synonyms/Alias Ras-related protein R-Ras3;
Gene Name MRAS
Gene Synonyms/Alias RRAS3;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
84MREQYMRTGDGFLIVPhosphoSitePlus22135298
Sequence
(Fasta)
MATSAVPSDN LPTYKLVVVG DGGVGKSALT IQFFQKIFVP DYDPTIEDSY LKHTEIDNQW 60
AILDVLDTAG QEEFSAMREQ YMRTGDGFLI VYSVTDKASF EHVDRFHQLI LRVKDRESFP 120
MILVANKVDL MHLRKITREQ GKEMATKHNI PYIETSAKDP PLNVDKAFHD LVRVIRQQIP 180
EKSQKKKKKT KWRGDRATGT HKLQCVIL 209
Keyword

KW-0025--Alternative splicing
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0488--Methylation
KW-0547--Nucleotide-binding
KW-0636--Prenylation
KW-1185--Reference proteome

Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR020849--Small_GTPase_Ras

PROSITE

PS51421--RAS

Pfam

PF00071--Ras

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005622--C:intracellular
GO:0005886--C:plasma membrane
GO:0005525--F:GTP binding
GO:0030742--F:GTP-dependent protein binding
GO:0003924--F:GTPase activity
GO:0030036--P:actin cytoskeleton organization
GO:0007275--P:multicellular organismal development
GO:0007517--P:muscle organ development
GO:0007265--P:Ras protein signal transduction