| Tag |
Content |
| dbPAF ID |
dbPAF-0000755 |
| Uniprot Accession |
O14791; APOL1_HUMAN; A5PLQ4; B4DU12; E9PF24; O60804; Q5R3P7; Q5R3P8; Q96AB8; Q96PM4; Q9BQ03;
|
| Genbank Protein ID |
NP_001130012.1; NP_001130013.1; NP_003652.2; XP_005261853.1;
|
| Genbank Nucleotide ID |
NM_001136540.1; NM_001136541.1; NM_003661.3; XM_005261796.2;
|
| Protein Name |
Apolipoprotein L1 |
| Protein Synonyms/Alias |
Apolipoprotein L;Apo-L;ApoL;Apolipoprotein L-I;ApoL-I; |
| Gene Name |
APOL1 |
| Gene Synonyms/Alias |
APOL; |
| Organism |
Homo sapiens(Human) |
| NCBI Taxa ID |
9606 |
Functional Description
(View all) |
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.Functional Description
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. |
Phosphorylation Sites
|
dbPAF PTMs: 4 |
Sequence
(Fasta) | MEGAALLRVS VLCIWMSALF LGVGVRAEEA GARVQQNVPS GTDTGDPQSK PLGDWAAGTM 60
DPESSIFIED AIKYFKEKVS TQNLLLLLTD NEAWNGFVAA AELPRNEADE LRKALDNLAR 120
QMIMKDKNWH DKGQQYRNWF LKEFPRLKSE LEDNIRRLRA LADGVQKVHK GTTIANVVSG 180
SLSISSGILT LVGMGLAPFT EGGSLVLLEP GMELGITAAL TGITSSTMDY GKKWWTQAQA 240
HDLVIKSLDK LKEVREFLGE NISNFLSLAG NTYQLTRGIG KDIRALRRAR ANLQSVPHAS 300
ASRPRVTEPI SAESGEQVER VNEPSILEMS RGVKLTDVAP VSFFLVLDVV YLVYESKHLH 360
EGAKSETAEE LKKVAQELEE KLNILNNNYK ILQADQEL
399Fasta Sequence
>O14791|APOL1|Homo sapiens(Human)
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
|
| Keyword |
KW-0025--Alternative splicing
KW-0153--Cholesterol metabolism
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0225--Disease mutation
KW-0325--Glycoprotein
KW-0345--HDL
KW-0443--Lipid metabolism
KW-0445--Lipid transport
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0964--Secreted
KW-0732--Signal
KW-0753--Steroid metabolism
KW-1207--Sterol metabolism
KW-0813--Transport
|
| Interpro |
IPR008405--ApoL
|
| PROSITE |
|
| Pfam |
PF05461--ApoL
|
| Gene Ontology |
GO:0072562--C:blood microparticle
GO:0005576--C:extracellular region
GO:0005615--C:extracellular space
GO:0034364--C:high-density lipoprotein particle
GO:0031224--C:intrinsic component of membrane
GO:0034361--C:very-low-density lipoprotein particle
GO:0005254--F:chloride channel activity
GO:0008289--F:lipid binding
GO:1902476--P:chloride transmembrane transport
GO:0008203--P:cholesterol metabolic process
GO:0019835--P:cytolysis
GO:0045087--P:innate immune response
GO:0031640--P:killing of cells of other organism
GO:0006869--P:lipid transport
GO:0042157--P:lipoprotein metabolic process
GO:0006898--P:receptor-mediated endocytosis
|
