dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000751
Uniprot Accession O14782; KIF3C_HUMAN; O43544; Q4ZG18; Q53SX5; Q562F7;
Genbank Protein ID NP_002245.4;
Genbank Nucleotide ID NM_002254.6;
Protein Name Kinesin-like protein KIF3C
Protein Synonyms/Alias
Gene Name KIF3C
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Microtubule-based anterograde translocator for membranous organelles.
Phosphorylation Sites
 dbPAF PTMs: 20
PositionPeptidesSourceReferences ( PMIDs )
5---MASKTKASEALKPhosphoSitePlus22135298
8MASKTKASEALKVVAPhosphoSitePlus22135298
173ELKENPETGVYIKDLPhosphoSitePlus22135298
176ENPETGVYIKDLSSFPhosphoSitePlus22135298
181GVYIKDLSSFVTKNVPhosphoSitePlus22135298
182VYIKDLSSFVTKNVKPhosphoSitePlus;curated22135298; 23917254
268AGGAATPSSGGGGGGPhosphoSitePlus22135298
269GGAATPSSGGGGGGGPhosphoSitePlus22135298
291GERPKEASKINLSLSPhosphoSitePlus22135298
312AALAGNRSTHIPYRDPhosphoSitePlus22135298
317NRSTHIPYRDSKLTRPhosphoSitePlus22135298
323PYRDSKLTRLLQDSLHPRD 9;PhosphoSitePlus;curated20068231; 18988627; 22135298; 22817900
341AKTIMVATLGPASHSPhosphoSitePlus22135298
574TMELRGTYTSLQQEVPhosphoSitePlus22135298
585QQEVEVKTKKLKKLYdbPTM 3.0;HPRD 9;PhosphoSitePlus17924679; 16381945; 23193290; 18452278; 18988627; 22135298
679SQMKKRPTSAVGYKRPhosphoSitePlus22135298
680QMKKRPTSAVGYKRPPhosphoSitePlus22135298
684RPTSAVGYKRPISQYPhosphoSitePlus22135298
754SFLERPSTSKVRKSRdbPTM 3.0;PhosphoSitePlus21060948; 16381945; 23193290; 22135298
755FLERPSTSKVRKSRSdbPTM 3.0;PhosphoSitePlus21060948; 16381945; 23193290; 22135298
Sequence
(Fasta)		MASKTKASEA LKVVARCRPL SRKEEAAGHE QILTMDVKLG QVTLRNPRAA PGELPKTFTF 60
DAVYDASSKQ ADLYDETVRP LIDSVLQGFN GTVFAYGQTG TGKTYTMQGT WVEPELRGVI 120
PNAFEHIFTH ISRSQNQQYL VRASYLEIYQ EEIRDLLSKE PGKRLELKEN PETGVYIKDL 180
SSFVTKNVKE IEHVMNLGNQ TRAVGSTHMN EVSSRSHAIF IITVECSERG SDGQDHIRVG 240
KLNLVDLAGS ERQNKAGPNT AGGAATPSSG GGGGGGGSGG GAGGERPKEA SKINLSLSAL 300
GNVIAALAGN RSTHIPYRDS KLTRLLQDSL GGNAKTIMVA TLGPASHSYD ESLSTLRFAN 360
RAKNIKNKPQ VNEDPKDTLL REFQEEIARL KAQLEKRGML GKRPRRKSSR RKKAVSAPPG 420
YPEGPVIEAW VAEEEDDNNN NHRPPQPILE SALEKNMENY LQEQKERLEE EKAAIQDDRS 480
LVSEEKQKLL EEKEKMLEDL RREQQATELL AAKYKAMESK LLIGGRNIMD HTNEQQKMLE 540
LKRQEIAEQK RREREMQQEM MLRDEETMEL RGTYTSLQQE VEVKTKKLKK LYAKLQAVKA 600
EIQDQHDEYI RVRQDLEEAQ NEQTRELKLK YLIIENFIPP EEKNKIMNRL FLDCEEEQWK 660
FQPLVPAGVS SSQMKKRPTS AVGYKRPISQ YARVAMAMGS HPRYRAENIM FLELDVSPPA 720
VFEMEFSHDQ EQDPRALHME RLMRLDSFLE RPSTSKVRKS RSWCQSPQRP PPSTTHASLA 780
SASLRPATVA DHE 794
Keyword

KW-0002--3D-structure
KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-0621--Polymorphism
KW-1185--Reference proteome
Interpro

IPR027640--Kinesin-like_fam
IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
Pfam

PF00225--Kinesin
Gene Ontology

GO:0097542--C:ciliary tip
GO:0005829--C:cytosol
GO:0005871--C:kinesin complex
GO:0005874--C:microtubule
GO:0072372--C:primary cilium
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0003777--F:microtubule motor activity
GO:0003774--F:motor activity
GO:0019886--P:antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0007596--P:blood coagulation
GO:0030705--P:cytoskeleton-dependent intracellular transport
GO:0007018--P:microtubule-based movement
GO:0006996--P:organelle organization
GO:0072384--P:organelle transport along microtubule