dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000746 |
| Uniprot Accession | O14772; FPGT_HUMAN; A6NMH3; B4DRX2; B4E2Y7; E9PNQ2; Q8N5J7; |
| Genbank Protein ID | NP_001186257.2; NP_001186258.2; NP_003829.3; |
| Genbank Nucleotide ID | NM_001199328.2; NM_001199329.2; NM_003838.4; |
| Protein Name | Fucose-1-phosphate guanylyltransferase |
| Protein Synonyms/Alias | GDP-L-fucose diphosphorylase;GDP-L-fucose pyrophosphorylase; |
| Gene Name | FPGT |
| Gene Synonyms/Alias | GFPP; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Catalyzes the formation of GDP-L-fucose from GTP and L-fucose-1-phosphate. Functions as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MAAARDPPEV SLREATQRKL RRFSELRGKL VARGEFWDIV AITAADEKQE LAYNQQLSEK 60 LKRKELPLGV QYHVFVDPAG AKIGNGGSTL CALQCLEKLY GDKWNSFTIL LIHSGGYSQR 120 LPNASALGKI FTALPLGNPI YQMLELKLAM YIDFPLNMNP GILVTCADDI ELYSIGEFEF 180 IRFDKPGFTA LAHPSSLTIG TTHGVFVLDP FDDLKHRDLE YRSCHRFLHK PSIEKMYQFN 240 AVCRPGNFCQ QDFAGGDIAD LKLDSDYVYT DSLFYMDHKS AKMLLAFYEK IGTLSCEIDA 300 YGDFLQALGP GATVEYTRNT SNVIKEESEL VEMRQRIFHL LKGTSLNVVV LNNSKFYHIG 360 TTEEYLFYFT SDNSLKSELG LQSITFSIFP DIPECSGKTS CIIQSILDSR CSVAPGSVVE 420 YSRLGPDVSV GENCIISGSY ILTKAALPAH SFVCSLSLKM NRCLKYATMA FGVQDNLKKS 480 VKTLSDIKLL QFFGVCFLSC LDVWNLKVTE ELFSGNKTCL SLWTARIFPV CSSLSDSVIT 540 SLKMLNAVKN KSAFSLNSYK LLSIEEMLIY KDVEDMITYR EQIFLEISLK SSLM 595 |
| Keyword | KW-0025--Alternative splicing |
| Interpro | IPR012887--Fucokinase |
| PROSITE | |
| Pfam | PF07959--Fucokinase |
| Gene Ontology | GO:0005737--C:cytoplasm |