Tag |
Content |
dbPAF ID |
dbPAF-0000739 |
Uniprot Accession |
O14753; OVOL1_HUMAN; Q6PCB1; |
Genbank Protein ID |
NP_004552.2; |
Genbank Nucleotide ID |
NM_004561.3; |
Protein Name |
Putative transcription factor Ovo-like 1 |
Protein Synonyms/Alias |
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Gene Name |
OVOL1 |
Gene Synonyms/Alias |
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Organism |
Homo sapiens(Human) |
NCBI Taxa ID |
9606 |
Functional Description (View all) |
Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity).Functional Description
Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity).
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Phosphorylation Sites
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dbPAF PTMs: 4 Position | Peptides | Source | References ( PMIDs ) |
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103 | RDHGFLRTKMKVTLG | PhosphoSitePlus | 22135298 | 108 | LRTKMKVTLGDSPSG | PhosphoSitePlus | 22135298 | 114 | VTLGDSPSGDLFTCR | PhosphoSitePlus | 22135298 | 119 | SPSGDLFTCRVCQKA | PhosphoSitePlus | 22135298 |
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Sequence (Fasta) | MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA 60 LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC 120 RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD 180 KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP 240 LLRKTSKKVA VALQNTVTSL LQGSPHL
268Fasta Sequence
>O14753|OVOL1|Homo sapiens(Human) MPRAFLVKKPCVSTCKRNWSELPDEERGEIYVPVSLGFCPPQPYREPEPSVAEPPSCPLALNMSLRDSSYSMAPGPCVVAQLPSEDMGHLTDPQSRDHGFLRTKMKVTLGDSPSGDLFTCRVCQKAFTYQRMLNRHMKCHNDVKRHLCTYCGKGFNDTFDLKRHVRTHTGVRPYKCSLCDKAFTQRCSLESHLKKIHGVQQKYAYKERRAKLYVCEECGCTSESQEGHVLHLKEHHPDSPLLRKTSKKVAVALQNTVTSLLQGSPHL
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Keyword |
KW-0181--Complete proteome KW-0238--DNA-binding KW-0479--Metal-binding KW-0539--Nucleus KW-1185--Reference proteome KW-0677--Repeat KW-0804--Transcription KW-0805--Transcription regulation KW-0862--Zinc KW-0863--Zinc-finger
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Interpro |
IPR027775--C2H2_Znf_fam IPR027755--TF_Ovo-like IPR007087--Znf_C2H2 IPR015880--Znf_C2H2-like IPR013087--Znf_C2H2/integrase_DNA-bd
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PROSITE |
PS00028--ZINC_FINGER_C2H2_1 PS50157--ZINC_FINGER_C2H2_2
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Pfam |
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Gene Ontology |
GO:0005634--C:nucleus GO:0046872--F:metal ion binding GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0008544--P:epidermis development GO:0051729--P:germline cell cycle switching, mitotic to meiotic cell cycle GO:0001822--P:kidney development GO:0007498--P:mesoderm development GO:1901994--P:negative regulation of meiotic cell cycle phase transition GO:2000647--P:negative regulation of stem cell proliferation GO:0043588--P:skin development GO:0007283--P:spermatogenesis GO:0006366--P:transcription from RNA polymerase II promoter
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