dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000739
Uniprot Accession O14753; OVOL1_HUMAN; Q6PCB1;
Genbank Protein ID NP_004552.2;
Genbank Nucleotide ID NM_004561.3;
Protein Name Putative transcription factor Ovo-like 1
Protein Synonyms/Alias
Gene Name OVOL1
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity).
Phosphorylation Sites
dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
103RDHGFLRTKMKVTLGPhosphoSitePlus22135298
108LRTKMKVTLGDSPSGPhosphoSitePlus22135298
114VTLGDSPSGDLFTCRPhosphoSitePlus22135298
119SPSGDLFTCRVCQKAPhosphoSitePlus22135298
Sequence
(Fasta)
MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA 60
LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC 120
RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD 180
KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP 240
LLRKTSKKVA VALQNTVTSL LQGSPHL 268
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027775--C2H2_Znf_fam
IPR027755--TF_Ovo-like
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd

PROSITE

PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam
Gene Ontology

GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001078--F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0008544--P:epidermis development
GO:0051729--P:germline cell cycle switching, mitotic to meiotic cell cycle
GO:0001822--P:kidney development
GO:0007498--P:mesoderm development
GO:1901994--P:negative regulation of meiotic cell cycle phase transition
GO:2000647--P:negative regulation of stem cell proliferation
GO:0043588--P:skin development
GO:0007283--P:spermatogenesis
GO:0006366--P:transcription from RNA polymerase II promoter