dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000735
Uniprot Accession O14737; PDCD5_HUMAN; B4DE64; Q53YC9; Q6IB70;
Genbank Protein ID NP_004699.1; XP_005259449.1;
Genbank Nucleotide ID NM_004708.3; XM_005259392.3;
Protein Name Programmed cell death protein 5
Protein Synonyms/Alias TF-1 cell apoptosis-related protein 19;Protein TFAR19;
Gene Name PDCD5
Gene Synonyms/Alias TFAR19;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May function in the process of apoptosis.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
42REAEMRNSILAQVLDPhosphoSitePlus;curated22135298; 25850435
51LAQVLDQSARARLSNPhosphoSitePlus;curated22135298; 23186163; 20873877; 23663014
57QSARARLSNLALVKPPhosphoSitePlus;curated22135298; 23186163
73KTKAVENYLIQMARYdbPTM 3.0;PhosphoSitePlus;curated20007894; 16381945; 23193290; 22135298; 22817900
80YLIQMARYGQLSEKVdbPTM 3.0;PhosphoSitePlus;curated20736484; 16381945; 23193290; 22135298; 22817900
88GQLSEKVSEQGLIEIPhosphoSitePlus22135298
103LKKVSQQTEKTTTVKdbPTM 3.0;HPRD 9;curated20068231; 16381945; 23193290; 18988627
119NRRKVMDSDEDDDY-dbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated15302935; 17081983; 18318008; 18669648; 19413330; 19690332;
125DSDEDDDY-------dbPTM 3.0;PhosphoSitePlus;curated18083107; 16381945; 23193290; 22135298; 26074081
Sequence
(Fasta)		MADEELEALR RQRLAELQAK HGDPGDAAQQ EAKHREAEMR NSILAQVLDQ SARARLSNLA 60
LVKPEKTKAV ENYLIQMARY GQLSEKVSEQ GLIEILKKVS QQTEKTTTVK FNRRKVMDSD 120
EDDDY 126
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR002836--PDCD5-related
PROSITE
Pfam

PF01984--dsDNA_bind
Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0010698--F:acetyltransferase activator activity
GO:0048487--F:beta-tubulin binding
GO:0003677--F:DNA binding
GO:0008201--F:heparin binding
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:1903645--P:negative regulation of chaperone-mediated protein folding
GO:0043065--P:positive regulation of apoptotic process
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010628--P:positive regulation of gene expression
GO:1903638--P:positive regulation of protein import into mitochondrial outer membrane
GO:0090200--P:positive regulation of release of cytochrome c from mitochondria