dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000731
Uniprot Accession O14730; RIOK3_HUMAN; Q8IXN9;
Genbank Protein ID NP_003822.2;
Genbank Nucleotide ID NM_003831.3;
Protein Name Serine/threonine-protein kinase RIO3
Protein Synonyms/Alias RIO kinase 3;sudD homolog;
Gene Name RIOK3
Gene Synonyms/Alias SUDD;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
8MDLVGVASPEPGTAAPhosphoSitePlus;curated22135298; 25627689; 23186163; 26074081
13VASPEPGTAAAWGPScurated22199227; 26074081
107EKKFNGDSKVSISFEPhosphoSitePlus22135298
110FNGDSKVSISFENYRPhosphoSitePlus22135298
112GDSKVSISFENYRKVPhosphoSitePlus;curated22135298; 25627689; 23898821; 23186163; 24961811
116VSISFENYRKVHPYEPhosphoSitePlus;curated22135298; 25627689
122NYRKVHPYEDSDSSEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 18691976; 20363803; 21406692;
125KVHPYEDSDSSEDEVdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;curated18669648; 16381945; 23193290; 20363803; 17081983; 18691976;
127HPYEDSDSSEDEVDWdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 20363803; 17081983; 18691976;
128PYEDSDSSEDEVDWQdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 20363803; 21406692; 17081983;
142QDTRDDPYRPAKPVPPhosphoSitePlus22135298
150RPAKPVPTPKKGFIGPhosphoSitePlus;curated22135298; 25627689; 21857030
505KNGRKAASFLKDDGDPhosphoSitePlus;curated22135298; 23186163; 22199227
517DGDPPLLYDE-----dbPTM 3.0;PhosphoSitePlus18083107; 16381945; 23193290; 22135298
Sequence
(Fasta)
MDLVGVASPE PGTAAAWGPS KCPWAIPQNT ISCSLADVMS EQLAKELQLE EEAAVFPEVA 60
VAEGPFITGE NIDTSSDLML AQMLQMEYDR EYDAQLRREE KKFNGDSKVS ISFENYRKVH 120
PYEDSDSSED EVDWQDTRDD PYRPAKPVPT PKKGFIGKGK DITTKHDEVV CGRKNTARME 180
NFAPEFQVGD GIGMDLKLSN HVFNALKQHA YSEERRSARL HEKKEHSTAE KAVDPKTRLL 240
MYKMVNSGML ETITGCISTG KESVVFHAYG GSMEDEKEDS KVIPTECAIK VFKTTLNEFK 300
NRDKYIKDDF RFKDRFSKLN PRKIIRMWAE KEMHNLARMQ RAGIPCPTVV LLKKHILVMS 360
FIGHDQVPAP KLKEVKLNSE EMKEAYYQTL HLMRQLYHEC TLVHADLSEY NMLWHAGKVW 420
LIDVSQSVEP THPHGLEFLF RDCRNVSQFF QKGGVKEALS ERELFNAVSG LNITADNEAD 480
FLAEIEALEK MNEDHVQKNG RKAASFLKDD GDPPLLYDE
Keyword

KW-0025--Alternative splicing
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000687--RIO_kinase
IPR018935--RIO_kinase_CS
IPR017406--Ser/Thr_kinase_Rio3

PROSITE

PS01245--RIO1

Pfam
Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0007059--P:chromosome segregation