dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000728
Uniprot Accession O14715; RGPD8_HUMAN; Q5CZA8;
Genbank Protein ID NP_001157935.1;
Genbank Nucleotide ID NM_001164463.1;
Protein Name RANBP2-like and GRIP domain-containing protein 8
Protein Synonyms/Alias Ran-binding protein 2-like 3;RanBP2-like 3;RanBP2L3;
Gene Name RGPD8
Gene Synonyms/Alias RANBP2ALPHA;RANBP2L1;RANBP2L3;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 48 (View all)
PositionPeptidesSourceReferences ( PMIDs )
19VASVLGLTPSPRQKSPhospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 18988627; 22135298; 19366988; 25627689; 22817900
21SVLGLTPSPRQKSMKPhospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 19413330; 18988627; 21081558; 22135298; 19366988;
26TPSPRQKSMKGFYFAPhosphoSitePlus22135298
128AAKLFPGSPAIYKLKdbPTM 3.022115753; 16381945; 23193290
261ENRELLESFDSALQSPhosphoSitePlus22135298
264ELLESFDSALQSAKSPhosphoSitePlus22135298
363GHMLLSLSRGKQDFLcurated22817900
599SFYGQLEYIGRSVHYPhosphoSitePlus22135298
606YIGRSVHYWKKVLPLPhosphoSitePlus22135298
700DIENDALSPEEQEECPhosphoSitePlus22135298
756VMQELEDYSEGGPLYPhosphoSitePlus22135298
757MQELEDYSEGGPLYKPhosphoSitePlus22135298
763YSEGGPLYKNGSLRNPhosphoSitePlus22135298
767GPLYKNGSLRNADSEcurated25627689
785STPSPTKYSLSPSKSPhosphoSitePlus22135298
786TPSPTKYSLSPSKSYPhosphoSitePlus22135298
788SPTKYSLSPSKSYKYdbPTM 3.0;PhosphoSitePlus18669648; 19276368; 20068230; 20068231; 21659604; 16381945;
790TKYSLSPSKSYKYSPPhosphoSitePlus22135298
792YSLSPSKSYKYSPETPhosphoSitePlus22135298
795SPSKSYKYSPETPPRPhosphoSitePlus22135298
Sequence
(Fasta)
MRRSKADVER YVASVLGLTP SPRQKSMKGF YFAKLYYEAK EYDLAKKYIC TYINVQERDP 60
KAHRFLGLLY ELEENTEKAV ECYRRSVELN PTQKDLVLKI AELLCKNDVT DGRAKYWVER 120
AAKLFPGSPA IYKLKEQLLD CEGEDGWNKL FDLIQSELYV RPDDVHVNIR LVELYRSTKR 180
LKDAVAHCHE AERNIALRSS LEWNSCVVQT LKEYLESLQC LESDKSDWRA TNTDLLLAYA 240
NLMLLTLSTR DVQENRELLE SFDSALQSAK SSLGGNDELS ATFLEMKGHF YMYAGSLLLK 300
MGQHGNNVQW RALSELAALC YLIAFQVPRP KIKLREGKAG QNLLEMMACD RLSQSGHMLL 360
SLSRGKQDFL KEVVETFANK IGQSALYDAL FSSQSPKDTS FLGSDDIGKI DVQEPELEDL 420
ARYDVGAIRA HNGSLQHLTW LGLQWNSLPA LPGIRKWLKQ LFHRLPHETS RLETNAPESI 480
CILDLEVFLL GVVYTSHLQL KEKCNSHHSS YQPLCLPFPV CKQLCTERQK SWWDAVCTLI 540
HRKAVPGNLA KLRLLVQHEI NTLRAQEKHG LQPALLVHWA KYLQKTGSGL NSFYGQLEYI 600
GRSVHYWKKV LPLLKIIKKN SIPEPIDPLF KHFHSVDIQA SEIVEYEEDA HITFAILDAV 660
NGNIEDAVTA FESIKSVVSY WNLALIFHRK AEDIENDALS PEEQEECRNY LTKTRDYLIK 720
IIDDGDSNLS VVKKLPVPLE SVKQMLNSVM QELEDYSEGG PLYKNGSLRN ADSEIKHSTP 780
SPTKYSLSPS KSYKYSPETP PRWTEDRNSL LNMICQQVEA IKKEMQELKL NSSKSASRHR 840
WPTENYGPDS VPDGYQGSQT FHGAPLTVAT TGPSVYYSQS PAYNSQYLLR PAANVTPTKG 900
SSNTEFKSTK EGFSIPVSAD GFKFGISEPG NQEKKREKPL ENDTGLQAQD IRGRKKGRGV 960
IFGQTSSTFT FADVAKSTSG EGFQFGKKDL NFKGFSGAGE KLFSSRYGKM ANKANTSGDF 1020
EKDDDAYKTE DSDDIHFEPV VQMPEKVELV TGEEGEKVLY SQGVKLFRFD AEVRQWKERG 1080
LGNLKILKNE VNGKLRMLMR REQVLKVCAN HWITTTMNLK PLSGSDRAWM WSASDFSDGD 1140
AKLERLAAKF KTPELAEEFK QKFEECQRLL LDIPLQTPHK LVDTGRAAKL IQRAEEMKSG 1200
LKDFKTFLTN DQTKVTEEEN KGSGTGVAGA SDTTIKPNAE NTGPTLEWDN YDLREDALDD 1260
SVSSSSVHAS PLASSPVRKN LFRFDESTTG SNFSFKSALS LSKSPAKLNQ SGTSVGTDEE 1320
SVVTQEEERD GQYFEPVVPL PDLVEVSSGE ENEQVVFSHR AEIYRYDKDV GQWKERGIGD 1380
IKILQNYDNK QVRIVMRRDQ VLKLCANHRI TPDMSLQNMK GTERVWVWTA CDFADGERKV 1440
EHLAVRFKLQ DVADSFKKIF DEAKTAQEKD SLITPHVSRS STPRESPCGK IAVAVLEEIT 1500
RERTDVIQGD DVADAASEVE VSSTSETTTK AVVSPPKFVF VSESVKRIFS SEKSKPFAFG 1560
NSSATGSLFG FSFNAPLKSN NSETSSVAQS GSESKVEPKK CELSKNSDIE QSSDSKVKNL 1620
SASFPTEESS INYTFKTPEK EPPLWHAEFT KEELVQKLRS TTKSADHLNG LLREIEATNA 1680
VLMEQIKLLK SEIRRLERNQ EREKSAANLE YLKNVLLQFI FLKPGSERER LLPVINTMLQ 1740
LSPEEKGKLA AVAQDEEENP SRSSG 1766
Keyword

KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR032023--GCC2_Rab_bind
IPR000237--GRIP
IPR011993--PH/PTB_dom
IPR000156--Ran_bind_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR001440--TPR_1
IPR019734--TPR_repeat

PROSITE

PS50913--GRIP
PS50196--RANBD1
PS50005--TPR
PS50293--TPR_REGION

Pfam

PF01465--GRIP
PF16704--Rab_bind
PF00638--Ran_BP1
PF00515--TPR_1

Gene Ontology

GO:0005643--C:nuclear pore
GO:0008536--F:Ran GTPase binding
GO:0000042--P:protein targeting to Golgi