dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000726
Uniprot Accession O14709; ZN197_HUMAN; B2RAH8; Q86VG0;
Genbank Protein ID NP_001020026.1; NP_008922.1; XP_005264840.1; XP_011547029.1;
Genbank Nucleotide ID NM_001024855.1; NM_006991.3; XM_005264783.3; XM_011548727.1;
Protein Name Zinc finger protein 197
Protein Synonyms/Alias Zinc finger protein with KRAB and SCAN domains 9;ZnF20;pVHL-associated KRAB domain-containing protein;
Gene Name ZNF197
Gene Synonyms/Alias ZKSCAN9;ZNF166;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
May be involved in transcriptional regulation.
Phosphorylation Sites
dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
50LHFRQLRYHETSGPQPhosphoSitePlus22135298
53RQLRYHETSGPQEALPhosphoSitePlus22135298
54QLRYHETSGPQEALSPhosphoSitePlus22135298
61SGPQEALSRLRELCRPhosphoSitePlus22135298
146DTLQKVVSAPGTTLPPhosphoSitePlus22135298
159LPPVLPGSHIAAEICPhosphoSitePlus22135298
284ADSHKGTSKRLQGSVPhosphoSitePlus22135298
449LNHQRIHTGEKPYKCPhosphoSitePlus22135298
524KAFILKKSLILHQRIPhosphoSitePlus;curated22135298; 23186163
664KVFILKKSLILHQRFPhosphoSitePlus22135298
785IEHKRIHSGEKPYECPhosphoSitePlus22135298
841IAHQRIHTGEKPYACPhosphoSitePlus22135298
897MVHQRIHTGEKPYKCPhosphoSitePlus22135298
953VGHQRIHTGEKPYGCPhosphoSitePlus22135298
Sequence
(Fasta)
MTRENVAHNA LRQEGLVKGK DDTWKWGTSF QGSSSSVWET SHLHFRQLRY HETSGPQEAL 60
SRLRELCRRW LRPEARTKAQ ILELLVLEQF LSILPGEIRT WVQLHHPGSG EEAVALVEEL 120
QKDLDGPAIQ VPVLVKDQDT LQKVVSAPGT TLPPVLPGSH IAAEICPHPP TDLVAFNLQD 180
PQHDSPAPEA SALSQEENPR NQLMALMLLT AQPQELVMFE EVSVCFTSEE WACLGPIQRA 240
LYWDVMLENY GNVTSLEWET MTENEEVTSK PSSSQRADSH KGTSKRLQGS VPQVLDFEEE 300
CEWQVLASQW GNETDERADT VKKVSLCERD KKKRTPPEKQ GQKWKELGDS LTFGSAISES 360
LIGTEGKKFY KCDMCCKHFN KISHLINHRR IHTGEKPHKC KECGKGFIQR SSLLMHLRNH 420
SGEKPYKCNE CGKAFSQSAY LLNHQRIHTG EKPYKCKECG KGFYRHSGLI IHLRRHSGER 480
PYKCNECGKV FSQNAYLIDH QRLHKGEEPY KCNKCQKAFI LKKSLILHQR IHSGEKPYKC 540
DECGKTFAQT TYLIDHQRLH SAENPYKCKE CGKVFIRSKS LLLHQRVHTE KKTFGCKKCG 600
KIFSSKSNFI DHKRMHSREK PYKCTECGKA FTQSAYLFDH QRLHNGEKPY ECNECGKVFI 660
LKKSLILHQR FHTGENLYEC KDCGKVFGSN RNLIDHERLH NGEKPYECRE CGKTFIMSKS 720
FMVHQKLHTQ EKAYKCEDCG KAFSYNSSLL VHRRIHTGEK PFECSECGRA FSSNRNLIEH 780
KRIHSGEKPY ECDECGKCFI LKKSLIGHQR IHTREKSYKC NDCGKVFSYR SNLIAHQRIH 840
TGEKPYACSE CGKGFTYNRN LIEHQRIHSG EKTYECHVCR KVLTSSRNLM VHQRIHTGEK 900
PYKCNECGKD FSQNKNLVVH QRMHTGEKPY ECDKCRKSFT SKRNLVGHQR IHTGEKPYGC 960
NDCSKVFRQR KNLTVHQKIH TDEKPCECDV SEKEFSQTSN LHLQQKIHTI EEFSWLQNTN 1020
ESKIEIQKI
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001909--KRAB
IPR008916--Retrov_capsid_C
IPR003309--SCAN_dom
IPR007087--Znf_C2H2
IPR015880--Znf_C2H2-like
IPR013087--Znf_C2H2/integrase_DNA-bd

PROSITE

PS50805--KRAB
PS50804--SCAN_BOX
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF01352--KRAB
PF02023--SCAN
PF00096--zf-C2H2
PF13912--zf-C2H2_6

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated