dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000705
Uniprot Accession O14639; ABLM1_HUMAN; A6NI16; A6NJ06; A8MXA9; B3KVH2; Q15039; Q5JVV1; Q5JVV2; Q5T6N2; Q5T6N3; Q5T6N5; Q68CQ9; Q9BUP1;
Genbank Protein ID NP_001003407.1; NP_001003408.1; NP_002304.3; NP_006711.3; XP_005269875.1; XP_005269885.1;
Genbank Nucleotide ID NM_001003407.1; NM_001003408.1; NM_002313.5; NM_006720.3; XM_005269818.1; XM_005269828.3;
Protein Name Actin-binding LIM protein 1
Protein Synonyms/Alias
Gene Name ABLIM1
Gene Synonyms/Alias ABLIM;KIAA0059;LIMAB1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.
Phosphorylation Sites
 dbPAF PTMs: 75 (View all)
PositionPeptidesSourceReferences ( PMIDs )
22SSEKSKVTSSERTSAPhosphoSitePlus22135298
28VTSSERTSARGSNRKPhosphoSitePlus22135298
214QLCAQPMSSSPKETTcurated25627689
215LCAQPMSSSPKETTFdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated19664995; 16381945; 23193290; 18988627; 22135298; 25627689
216CAQPMSSSPKETTFSPhosphoSitePlus;curated22135298; 25627689
307GDKHYHPSCARCSRCdbPTM 3.018669648; 20068231; 16381945; 23193290
325FTEGEEMYLQGSTVWdbPTM 3.015144186; 19901323; 16381945; 23193290
349TEEKLRPTRTSSESIPhosphoSitePlus22135298
351EKLRPTRTSSESIYSPhosphoSitePlus;curated22135298; 25627689; 23898821; 23403867; 19690332
352KLRPTRTSSESIYSRdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated17081983; 16381945; 23193290; 18988627; 22135298; 19366988;
353LRPTRTSSESIYSRPdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 20007894; 18988627; 19060867;
355PTRTSSESIYSRPGSdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated17081983; 16381945; 23193290; 18988627; 22135298; 19366988;
357RTSSESIYSRPGSSIdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated15144186; 16381945; 23193290; 14729942; 15570572; 18083107;
358TSSESIYSRPGSSIPdbPTM 3.0;PhosphoSitePlus;curated19276368; 16381945; 23193290; 22135298; 23186163; 26267517
362SIYSRPGSSIPGSPGdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated18669648; 16381945; 23193290; 17081983; 20068231; 18988627;
363IYSRPGSSIPGSPGHdbPTM 3.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated17081983; 16381945; 23193290; 18988627; 22135298; 19366988;
367PGSSIPGSPGHTIYAdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PHOSIDA;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated19690332; 16381945; 23193290; 18669648; 19276368; 20363803;
371IPGSPGHTIYAKVDNdbPTM 3.0;PhosphoSitePlus;curated15570572; 16381945; 23193290; 22135298; 23663014; 26074081
373GSPGHTIYAKVDNEIdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;UniProt;curated15144186; 19690332; 16381945; 23193290; 14729942; 18083107;
383VDNEILDYKDLAAIPdbPTM 3.0;PhosphoSitePlus;curated18180459; 20007894; 20736484; 16381945; 23193290; 22135298;
Sequence
(Fasta)		MPAFLGLKCL GKLCSSEKSK VTSSERTSAR GSNRKRLIVE DRRVSGTSFT AHRRATITHL 60
LYLCPKDYCP RGRVCNSVDP FVAHPQDPHH PSEKPVIHCH KCGEPCKGEV LRVQTKHFHI 120
KCFTCKVCGC DLAQGGFFIK NGEYLCTLDY QRMYGTRCHG CGEFVEGEVV TALGKTYHPN 180
CFACTICKRP FPPGDRVTFN GRDCLCQLCA QPMSSSPKET TFSSNCAGCG RDIKNGQALL 240
ALDKQWHLGC FKCKSCGKVL TGEYISKDGA PYCEKDYQGL FGVKCEACHQ FITGKVLEAG 300
DKHYHPSCAR CSRCNQMFTE GEEMYLQGST VWHPDCKQST KTEEKLRPTR TSSESIYSRP 360
GSSIPGSPGH TIYAKVDNEI LDYKDLAAIP KVKAIYDIER PDLITYEPFY TSGYDDKQER 420
QSLGESPRTL SPTPSAEGYQ DVRDRMIHRS TSQGSINSPV YSRHSYTPTT SRSPQHFHRP 480
GNEPSSGRNS PLPYRPDSRP LTPTYAQAPK HFHVPDQGIN IYRKPPIYKQ HAALAAQSKS 540
SEDIIKFSKF PAAQAPDPSE TPKIETDHWP GPPSFAVVGP DMKRRSSGRE EDDEELLRRR 600
QLQEEQLMKL NSGLGQLILK EEMEKESRER SSLLASRYDS PINSASHIPS SKTASLPGYG 660
RNGLHRPVST DFAQYNSYGD VSGGVRDYQT LPDGHMPAMR MDRGVSMPNM LEPKIFPYEM 720
LMVTNRGRNK ILREVDRTRL ERHLAPEVFR EIFGMSIQEF DRLPLWRRND MKKKAKLF 779
Keyword

KW-0009--Actin-binding
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
Interpro

IPR028448--ABLIM1
IPR032402--AbLIM_anchor
IPR003128--Villin_headpiece
IPR001781--Znf_LIM
PROSITE

PS51089--HP
PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
Pfam

PF16182--AbLIM_anchor
PF00412--LIM
PF02209--VHP
Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0030027--C:lamellipodium
GO:0097481--C:neuronal postsynaptic density
GO:0001725--C:stress fiber
GO:0003779--F:actin binding
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0042384--P:cilium assembly
GO:0007010--P:cytoskeleton organization
GO:0030032--P:lamellipodium assembly
GO:0009887--P:organ morphogenesis
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0007601--P:visual perception