dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000696
Uniprot Accession O14602; IF1AY_HUMAN; Q9BS77;
Genbank Protein ID NP_001265541.1; NP_004672.2;
Genbank Nucleotide ID NM_001278612.1; NM_004681.3;
Protein Name Eukaryotic translation initiation factor 1A, Y-chromosomal
Protein Synonyms/Alias
Gene Name EIF1AY
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
73RKKVWINTSDIILVGPhosphoSitePlus;curated22135298; 22199227
74KKVWINTSDIILVGLPhosphoSitePlus22135298
95KADVILKYNADEARSPhosphoSitePlus22135298
102YNADEARSLKAYGELPhosphoSitePlus;curated22135298; 25627689
106EARSLKAYGELPEHAPhosphoSitePlus22135298
Sequence
(Fasta)		MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAL CFDGVKRLCH 60
IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT 120
FGPGDDDEIQ FDDIGDDDED IDDI 145
Keyword

KW-0181--Complete proteome
KW-0396--Initiation factor
KW-1017--Isopeptide bond
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR012340--NA-bd_OB-fold
IPR006196--RNA-binding_domain_S1_IF1
IPR001253--TIF_eIF-1A
IPR018104--TIF_eIF-1A_CS
PROSITE

PS01262--IF1A
PS50832--S1_IF1_TYPE
Pfam

PF01176--eIF-1a
Gene Ontology

GO:0003743--F:translation initiation factor activity