dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0000691 |
| Uniprot Accession | O14593; RFXK_HUMAN; O95839; Q24JQ1; Q6FGA8; |
| Genbank Protein ID | NP_001265656.1; NP_001265657.1; NP_003712.1; NP_604389.1; XP_005260191.1; XP_005260192.1; |
| Genbank Nucleotide ID | NM_001278727.1; NM_001278728.1; NM_003721.3; NM_134440.2; XM_005260134.3; XM_005260135.2; |
| Protein Name | DNA-binding protein RFXANK |
| Protein Synonyms/Alias | Ankyrin repeat family A protein 1;Regulatory factor X subunit B;RFX-B;Regulatory factor X-associated ankyrin-containing protein; |
| Gene Name | RFXANK |
| Gene Synonyms/Alias | ANKRA1;RFXB; |
| Organism | Homo sapiens(Human) |
| NCBI Taxa ID | 9606 |
| Functional Description (View all) |
Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MELTQPAEDL IQTQQTPASE LGDPEDPGEE AADGSDTVVL SLFPCTPEPV NPEPDASVSS 60 PQAGSSLKHS TTLTNRQRGN EVSALPATLD SLSIHQLAAQ GELDQLKEHL RKGDNLVNKP 120 DERGFTPLIW ASAFGEIETV RFLLEWGADP HILAKERESA LSLASTGGYT DIVGLLLERD 180 VDINIYDWNG GTPLLYAVRG NHVKCVEALL ARGADLTTEA DSGYTPMDLA VALGYRKVQQ 240 VIENHILKLF QSNLVPADPE 261 |
| Keyword | KW-0002--3D-structure |
| Interpro | IPR002110--Ankyrin_rpt |
| PROSITE | |
| Pfam | |
| Gene Ontology | GO:0005737--C:cytoplasm |