dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000684
Uniprot Accession O14561; ACPM_HUMAN; B2R4M1; Q9UNV1;
Genbank Protein ID NP_004994.1;
Genbank Nucleotide ID NM_005003.2;
Protein Name Acyl carrier protein, mitochondrial
Protein Synonyms/Alias
Gene Name NDUFAB1
Gene Synonyms/Alias
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain (By similarity).
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
11RVLSAYVSRLPAAFAPhosphoSitePlus22135298
99KIDPEKLSVNSHFMKPhosphoSitePlus;curated22135298; 25627689; 23186163
147CPQEIVDYIADKKDVPhosphoSitePlus22135298
Sequence
(Fasta)
MASRVLSAYV SRLPAAFAPL PRVRMLAVAR PLSTALCSAG TQTRLGTLQP ALVLAQVPGR 60
VTQLCRQYSD MPPLTLEGIQ DRVLYVLKLY DKIDPEKLSV NSHFMKDLGL DSLDQVEIIM 120
AMEDEFGFEI PDIDAEKLMC PQEIVDYIAD KKDVYE 157
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0181--Complete proteome
KW-0903--Direct protein sequencing
KW-0249--Electron transport
KW-0275--Fatty acid biosynthesis
KW-0276--Fatty acid metabolism
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0496--Mitochondrion
KW-0596--Phosphopantetheine
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0679--Respiratory chain
KW-0809--Transit peptide
KW-0813--Transport

Interpro

IPR003231--Acyl_carrier
IPR009081--Acyl_carrier_prot-like
IPR006162--Ppantetheine_attach_site

PROSITE

PS50075--ACP_DOMAIN
PS00012--PHOSPHOPANTETHEINE

Pfam

PF00550--PP-binding

Gene Ontology

GO:0005743--C:mitochondrial inner membrane
GO:0005759--C:mitochondrial matrix
GO:0031966--C:mitochondrial membrane
GO:0005747--C:mitochondrial respiratory chain complex I
GO:0000036--F:ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process
GO:0005509--F:calcium ion binding
GO:0005504--F:fatty acid binding
GO:0008137--F:NADH dehydrogenase (ubiquinone) activity
GO:0044237--P:cellular metabolic process
GO:0006633--P:fatty acid biosynthetic process
GO:0006120--P:mitochondrial electron transport, NADH to ubiquinone
GO:0009249--P:protein lipoylation
GO:0022904--P:respiratory electron transport chain
GO:0044281--P:small molecule metabolic process