dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000670
Uniprot Accession O14523; C2C2L_HUMAN; Q86UT7; Q86V04; Q8N522; Q8TBN4; Q96G10;
Genbank Protein ID NP_001277403.1; NP_055622.3;
Genbank Nucleotide ID NM_001290474.1; NM_014807.4;
Protein Name C2 domain-containing protein 2-like
Protein Synonyms/Alias Transmembrane protein 24;
Gene Name C2CD2L
Gene Synonyms/Alias KIAA0285;TMEM24;DLNB23;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 40 (View all)
PositionPeptidesSourceReferences ( PMIDs )
59LAGEPAGSLRELGVWPhosphoSitePlus;curated22135298; 25850435; 23186163; 24117733
68RELGVWRSLLRLRATcurated23898821
358LKVLRSSSCGDTELLPhosphoPep 2.0;PhosphoSitePlus;curated19060867; 22135298; 23186163
374QATLPVGSPSRPLSRdbPTM 3.0;PhosphoSitePlus;curated19276368; 16381945; 23193290; 22135298; 23917254; 25849741
388RRQLCPLTPGPGKALPhosphoSitePlus;curated22135298; 25627689
411ELHYEEGSPRNLGTPdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoPep 2.0;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 19060867; 22135298;
417GSPRNLGTPTSSTPRdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 18988627; 22135298; 19366988;
420RNLGTPTSSTPRPSIdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.018669648; 16381945; 23193290; 18988627; 22135298; 19366988
421NLGTPTSSTPRPSITPhosphoSitePlus22135298
422LGTPTSSTPRPSITPPhosphoSitePlus;curated22135298; 25627689
426TSSTPRPSITPTKKIPhosphoSitePlus;curated22135298; 23186163
428STPRPSITPTKKIELPhosphoSitePlus;curated22135298; 25627689; 23917254; 26074081
430PRPSITPTKKIELDRdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.018669648; 16381945; 23193290; 18988627; 22135298; 19366988
464RIDGKLDSPSRSPSKdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;UniProt;curated18669648; 16381945; 23193290; 20363803; 18988627; 22135298;
466DGKLDSPSRSPSKVEdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18669648; 16381945; 23193290; 18988627; 22135298; 25850435;
468KLDSPSRSPSKVEVTdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;PhosphoSitePlus;SysPTM 2.0;curated18669648; 16381945; 23193290; 20363803; 18988627; 22135298;
470DSPSRSPSKVEVTEKPhosphoSitePlus;curated22135298; 22199227; 23186163; 23663014
475SPSKVEVTEKTTTVLdbPTM 3.0;Phospho.ELM 9.0;HPRD 9;curated18669648; 16381945; 23193290; 18988627; 23663014
483EKTTTVLSESSGPSNPhosphoSitePlus22135298
489LSESSGPSNTSHSSScurated25627689
Sequence
(Fasta)
MDPGWGQRDV GWAALLILFA ASLLTVFAWL LQYARGLWLA RARGDRGPGP ALAGEPAGSL 60
RELGVWRSLL RLRATRAGAA EEPGVRGLLA SLFAFKSFRE NWQRAWVRAL NEQACRNGSS 120
IQIAFEEVPQ LPPRASISHV TCVDQSEHTM VLRCQLSAEE VRFPVSVTQQ SPAAVSMETY 180
HVTLTLPPTQ LEVNLEEIPG EGLLISWAFT DRPDLSLTVL PKLQARERGE EQVELSTIEE 240
LIKDAIVSTQ PAMMVNLRAC SAPGGLVPSE KPPMMPQAQP AIPRPNRLFL RQLRASHLGN 300
ELEGTEELCC VAELDNPMQQ KWTKPARAGS EVEWTEDLAL DLGPQSRELT LKVLRSSSCG 360
DTELLGQATL PVGSPSRPLS RRQLCPLTPG PGKALGPAAT MAVELHYEEG SPRNLGTPTS 420
STPRPSITPT KKIELDRTIM PDGTIVTTVT TVQSRPRIDG KLDSPSRSPS KVEVTEKTTT 480
VLSESSGPSN TSHSSSRDSH LSNGLDPVAE TAIRQLTEPS GRVAKKTPTK RSTLIISGVS 540
KVPIAQDELA LSLGYAASLE ASVQDDAGTS GGPSSPPSDP PAMSPGPLDA LSSPTSVQEA 600
DETTRSDISE RPSVDDIESE TGSTGALETR SLKDHKVSFL RSGTKLIFRR RPRQKEAGLS 660
QSHDDLSNAT ATPSVRKKAG SFSRRLIKRF SFKSKPKANG NPSPQL 707
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000008--C2_dom

PROSITE
Pfam
Gene Ontology

GO:0016021--C:integral component of membrane
GO:0035774--P:positive regulation of insulin secretion involved in cellular response to glucose stimulus