dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000667
Uniprot Accession O14519; CDKA1_HUMAN; F5GYA4;
Genbank Protein ID NP_001257362.1; NP_001257363.1; NP_004633.1;
Genbank Nucleotide ID NM_001270433.1; NM_001270434.1; NM_004642.3;
Protein Name Cyclin-dependent kinase 2-associated protein 1
Protein Synonyms/Alias
Gene Name CDK2AP1
Gene Synonyms/Alias CDKAP1;DOC1;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)		 specific inhibitor of the cell-cycle kinase CDK2.
Phosphorylation Sites
 dbPAF PTMs: 7
PositionPeptidesSourceReferences ( PMIDs )
21AALNAAGSVHSPSTScurated25627689
24NAAGSVHSPSTSMATdbPTM 3.0;HPRD 9;PhosphoSitePlus;curated20068231; 16381945; 23193290; 18988627; 22135298; 25627689;
26AGSVHSPSTSMATSScurated25627689
27GSVHSPSTSMATSSQcurated25627689
28SVHSPSTSMATSSQYcurated25627689
46LSDYGPPSLGYTQGTdbPTM 3.0;PhosphoSitePlus22427660; 16381945; 23193290; 22135298
84IRPTYAGSKSAMERLPhosphoSitePlus22135298
Sequence
(Fasta)		MSYKPNLAAH MPAAALNAAG SVHSPSTSMA TSSQYRQLLS DYGPPSLGYT QGTGNSQVPQ 60
SKYAELLAII EELGKEIRPT YAGSKSAMER LKRGIIHARG LVRECLAETE RNARS 116
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-1015--Disulfide bond
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0043--Tumor suppressor
Interpro

IPR017266--CDK2-associated_2
IPR019187--Cyclin-dep_kinase2-assoc_pr
PROSITE
Pfam

PF09806--CDK2AP
Gene Ontology

GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0070182--F:DNA polymerase binding
GO:0007049--P:cell cycle
GO:0006261--P:DNA-dependent DNA replication
GO:0001934--P:positive regulation of protein phosphorylation