dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000655
Uniprot Accession O14490; DLGP1_HUMAN; A8MWN8; B2RMU8; B7WPA1; B7Z2H2; B7Z2I2; B7Z9Y4; O14489; P78335;
Genbank Protein ID NP_001003809.1; NP_001229690.1; NP_001229691.1; NP_001229692.1; NP_001229693.1; NP_001229694.1; NP_001229695.1; NP_004737.2;
Genbank Nucleotide ID NM_001003809.2; NM_001242761.1; NM_001242762.1; NM_001242763.1; NM_001242764.1; NM_001242765.1; NM_001242766.1; NM_004746.3;
Protein Name Disks large-associated protein 1
Protein Synonyms/Alias
Gene Name DLGAP1
Gene Synonyms/Alias DAP1;GKAP;
Organism Homo sapiens(Human)
NCBI Taxa ID 9606
Functional Description
(View all)
Part of the postsynaptic scaffold in neuronal cells.
Phosphorylation Sites
dbPAF PTMs: 28 (View all)
PositionPeptidesSourceReferences ( PMIDs )
7-MKGLSGSRSHHHGVPhosphoSitePlus22135298
24DSACDSLSHHSDRKPPhosphoSitePlus22135298
118LPLSRDGYHTLQYKRPhosphoSitePlus22135298
169SVNGGKASPDEAQAAcurated23898821
314ESCQQERSCQYLQVPPhosphoSitePlus22135298
317QQERSCQYLQVPQDEPhosphoSitePlus22135298
329QDEWTGYTPRGKDDEPhosphoSitePlus22135298
346CRRMRSGSYIKAMGDdbPTM 3.0;PhosphoSitePlus22117215; 16381945; 23193290; 22135298
347RRMRSGSYIKAMGDEPhospho.ELM 9.0;HPRD 9;PhosphoSitePlus;curated18083107; 18988627; 22135298; 22817900
375KVAARRESYLKATQPdbPTM 3.0;PhosphoSitePlus22117215; 16381945; 23193290; 22135298
406KLQIRSHSYLRAVSEdbPTM 3.0;PhosphoSitePlus22117215; 16381945; 23193290; 22135298
419SEVSINRSLDSLDPAcurated25850435
430LDPAGLLTSPKFRSRPhosphoPep 2.0;curated19060867; 22817900
431DPAGLLTSPKFRSRNPhosphoPep 2.0;curated19060867; 22817900
440KFRSRNESYMRAMSTdbPTM 3.0;PhosphoSitePlus22117215; 16381945; 23193290; 22135298
491PGCFRMRSHSYVRAIPhosphoSitePlus22135298
493CFRMRSHSYVRAIEKdbPTM 3.0;PhosphoSitePlus22117215; 16381945; 23193290; 22135298
515CVSLRSSSPPRTTTTcurated23898821
530VRTIQSSTVSSCITTdbPTM 3.0;PhosphoSitePlus;SysPTM 2.0;curated16674116; 16381945; 23193290; 22135298; 19366988; 22817900
536STVSSCITTYKKTPPdbPTM 3.0;PhosphoSitePlus;SysPTM 2.0;curated16674116; 16381945; 23193290; 22135298; 19366988; 22817900
Sequence
(Fasta)
MKGLSGSRSH HHGVTCDSAC DSLSHHSDRK PYLLSPVEHH PADHPYYTQR NSFQAECVGP 60
FSDPLASSTF PRRHYTSQQE LKDECALVPR TLATKANRIP ANLLDQFERQ LPLSRDGYHT 120
LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DEAQAARYGK 180
RSKSKERRAE PKARPSTSPG WWSSDDNLDG DMCIYHAPSG VMTMGRCPDR SASQYFLEAY 240
NTISEQAVKA SRSNNDVKCS TCANLPVSLD TPLLKKSAWS STLTVSRARE VYQKASVNMD 300
QAMVKSESCQ QERSCQYLQV PQDEWTGYTP RGKDDEIPCR RMRSGSYIKA MGDEDSGDSD 360
TSPKPSPKVA ARRESYLKAT QPSLTELTTL KISNEHSPKL QIRSHSYLRA VSEVSINRSL 420
DSLDPAGLLT SPKFRSRNES YMRAMSTISQ VSEMEVNGQF ESVCESVFSE LESQAVEALD 480
LPMPGCFRMR SHSYVRAIEK GCSQDDECVS LRSSSPPRTT TTVRTIQSST VSSCITTYKK 540
TPPPVPPRTT TKPFISITAQ SSTESAQDAY MDGQGQRGDI ISQSGLSNST ESLDSMKALT 600
AAIEAANAQI HGPASQHMGN NTATVTTTTT IATVTTEDRK KDHFKKNRCL SIGIQVDDAE 660
EPDKTGENKA PSKFQSVGVQ VEEEKCFRRF TRSNSVTTAV QADLDFHDNL ENSLESIEDN 720
SCPGPMARQF SRDASTSTVS IQGSGNHYHA CAADDDFDTD FDPSILPPPD PWIDSITEDP 780
LEAVQRSVCH RDGHWFLKLL QAERDRMEGW CQQMEREERE NNLPEDILGK IRTAVGSAQL 840
LMAQKFYQFR ELCEENLNPN AHPRPTSQDL AGFWDMLQLS IENISMKFDE LHQLKANNWK 900
QMDPLDKKER RAPPPVPKKP AKGPAPLIRE RSLESSQRQE ARKRLMAAKR AASVRQNSAT 960
ESAESIEIYI PEAQTRL 978
Keyword

KW-0025--Alternative splicing
KW-0965--Cell junction
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-0628--Postsynaptic cell membrane
KW-1185--Reference proteome
KW-0770--Synapse

Interpro

IPR030524--DLGAP1
IPR005026--SAPAP

PROSITE
Pfam

PF03359--GKAP

Gene Ontology

GO:0030054--C:cell junction
GO:0097481--C:neuronal postsynaptic density
GO:0045211--C:postsynaptic membrane
GO:0007268--P:synaptic transmission