dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0000652
Uniprot Accession O14467; MBF1_YEAST; D6W2Z8; Q7LGJ8; Q86ZS7;
Genbank Protein ID NP_014942.4;
Genbank Nucleotide ID NM_001184346.3;
Protein Name Multiprotein-bridging factor 1
Protein Synonyms/Alias Suppressor of frameshift mutations protein 13;
Gene Name MBF1
Gene Synonyms/Alias SUF13;YOR298C-A;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Transcriptional coactivator that stimulates GCN4-dependent transcriptional activity by bridging the DNA-binding region of GCN4 and TBP (SPT15), thereby recruiting TBP to GCN4-bound promoters.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
2------MSDWDTNTIPHOSIDA;curated21081558; 26040406; 26040289; 19795423
6--MSDWDTNTIIGSRcurated26040289
8MSDWDTNTIIGSRARcurated26040289; 22817900; 19547744
28PRANVARSQGQINAAPhosphoGRID 2.0;PhosphoPep 2.0;curated21177495; 21126336; 19060867; 22369663; 22817900; 25315811
43RRQGLVVSVDKKYGScurated25315811
50SVDKKYGSTNTRGDNPhosphoGRID 2.019779198
108TKINEKPTVVNDYEAdbPTM 3.0;PhosphoGRID 2.0;curated18407956; 16381945; 23193290
126IPNQQVLSKLERALGcurated22369663; 25315811
143LRGNNIGSPLGAPKKdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17287358; 17330950; 17563356; 18407956; 16381945;
Sequence
(Fasta)		MSDWDTNTII GSRARAGGSG PRANVARSQG QINAARRQGL VVSVDKKYGS TNTRGDNEGQ 60
RLTKVDRETD IVKPKKLDPN VGRAISRART DKKMSQKDLA TKINEKPTVV NDYEAARAIP 120
NQQVLSKLER ALGVKLRGNN IGSPLGAPKK K 152
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR001387--Cro/C1-type_HTH
IPR010982--Lambda_DNA-bd_dom
IPR013729--MBF1_N
PROSITE

PS50943--HTH_CROC1
Pfam

PF01381--HTH_3
PF08523--MBF1
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated