dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000649
Uniprot Accession O14370; BCA1_SCHPO; O94352;
Genbank Protein ID NP_595180.2;
Genbank Nucleotide ID NM_001021088.2;
Protein Name Branched-chain-amino-acid aminotransferase, mitochondrial
Protein Synonyms/Alias
Gene Name eca39
Gene Synonyms/Alias SPBC428.02c;SPBC582.12c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
105NREKGWSTPEIVPFGdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSLMFLRRAG NIKGRNIRFA LQRGSVGYSQ QSSEACKNFL NTTQLRTMVQ TAALHGPKPM 60
DSSHIKVTNV KELKPLPEWK SLKFGENFTD HMLIMKWNRE KGWSTPEIVP FGKLCFHPAS 120
SVFHYGFECF EGMKAFRDEK GVPRLFRPIK NAERMLSTGT RISLPSFDPA ELAEIIRKFV 180
AHENRWVPDQ RGYSLYIRPT FIGTDEALGV HHCDNAMLYV IASPVGPYYS SGFKAVKLCC 240
SEESVRAWPG GTGHYKLGGN YAPSVLPQKE AAKKGYAQIL WLYGDEDYIT EVGTMNCFTV 300
WINKNGEKEI ITAPLDGMIL PGVTRDSILE ICRERLAPKG WKITEGKYSM KEVAQASKEG 360
RLLEVFGAGT AALVSPVKAI NYKGTEYEIP MPEGQEAGPI TSEISKWILD IQYGKEPNNP 420
WSVPALP 428
Keyword

KW-0028--Amino-acid biosynthesis
KW-0032--Aminotransferase
KW-0100--Branched-chain amino acid biosynthesis
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0496--Mitochondrion
KW-0539--Nucleus
KW-0663--Pyridoxal phosphate
KW-1185--Reference proteome
KW-0808--Transferase
KW-0809--Transit peptide

Interpro

IPR001544--Aminotrans_IV
IPR018300--Aminotrans_IV_CS
IPR005786--B_amino_transII

PROSITE

PS00770--AA_TRANSFER_CLASS_4

Pfam

PF01063--Aminotran_4

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005759--C:mitochondrial matrix
GO:0005634--C:nucleus
GO:0052656--F:L-isoleucine transaminase activity
GO:0052654--F:L-leucine transaminase activity
GO:0052655--F:L-valine transaminase activity
GO:0030170--F:pyridoxal phosphate binding
GO:0009097--P:isoleucine biosynthetic process
GO:0009098--P:leucine biosynthetic process
GO:0009099--P:valine biosynthetic process