dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0000645
Uniprot Accession O14362; SMI1_SCHPO;
Genbank Protein ID NP_596268.1;
Genbank Nucleotide ID NM_001022189.2;
Protein Name Cell wall biosynthesis/cell cycle regulator smi1
Protein Synonyms/Alias
Gene Name smi1
Gene Synonyms/Alias SPBC30D10.17c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Protein involved in the regulation of cell wall assembly and 1,3-beta-glucan synthesis, possibly through the transcriptional regulation of cell wall glucan and chitin synthesis (By similarity). Involved in cellullar response to nitrogen starvation and required for quiescence-maintenance by regulating negatively G0 to G1 transition.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
500EKEIETTSVKQE---dbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MSKNSFSSMA NSVTSFFQSL TTPNRHADPS FRPSRREKQS RLPTPLQSVA ASAYSGVNAS 60
QTGLLNDSRA NSVTNLPNSS NTSQVGLNNI SPAPVGYVPG SKTNELANNS MEMQEISPNG 120
SASLPPPVSE SWRRIDRWAE ENYYELYCQL CYGATVADVD SLEYELECTL PRDVRESLYI 180
HDGQDRGGQP TGILFGVTLL DIEEIEEESE LWRRVAQSYA EATLAGKIDQ AVASRQASFP 240
PGAVQCVYAH PGWIPLAKDF VGNNIAIDLA PGPAGQWGQV ILFGRDQDTK YVVARSWADF 300
LAIVAYDMEN GKWLVDEDDN SLRLIYGPPR EQWSYLDILK YRARKAERRK FKKRDGKRTT 360
RPIPKSIAKE DVTNSANSTA PSTGTTVLDD GLDNNYEDIP LYGPSKDEEL IKKEELEADT 420
DLGLINTSEI NQPANLPDEP TAETSNPVSA TTVEAVTTTA DNKDEEKNDH VTEDVSQNST 480
IAEASSLQAQ EEEKEIETTS VKQE 505
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0961--Cell wall biogenesis/degradation
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0498--Mitosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR018958--SMI1/KNR4-like_dom

PROSITE
Pfam

PF09346--SMI1_KNR4

Gene Ontology

GO:0032153--C:cell division site
GO:0030428--C:cell septum
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0051301--P:cell division
GO:0071555--P:cell wall organization
GO:0007067--P:mitotic nuclear division
GO:0070317--P:negative regulation of G0 to G1 transition
GO:0032995--P:regulation of fungal-type cell wall biogenesis
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated